2018 Section 5 - Rhinology and Allergic Disorders

STEVENS ET AL

J ALLERGY CLIN IMMUNOL VOLUME 136, NUMBER 6

53. Kalfa VC, Spector SL, Ganz T, Cole AM. Lysozyme levels in the nasal secretions of patients with perennial allergic rhinitis and recurrent sinusitis. Ann Allergy Asthma Immunol 2004;93:288-92 . 54. Seshadri S, Lin DC, Rosati M, Carter RG, Norton JE, Suh L, et al. Reduced expression of antimicrobial PLUNC proteins in nasal polyp tissues of patients with chronic rhinosinusitis. Allergy 2012;67:920-8 . 55. Clamp JR, Creeth JM. Some non-mucin components of mucus and their possible biological roles. Ciba Found Symp 1984;109:121-36 . 56. Legrand D. Lactoferrin, a key molecule in immune and inflammatory processes. Biochem Cell Biol 2012;90:252-68 . 57. Sano H, Nagai K, Tsutsumi H, Kuroki Y. Lactoferrin and surfactant protein A exhibit distinct binding specificity to F protein and differently modulate respiratory syncytial virus infection. Eur J Immunol 2003;33:2894-902 . 58. Psaltis AJ, Wormald PJ, Ha KR, Tan LW. Reduced levels of lactoferrin in biofilm-associated chronic rhinosinusitis. Laryngoscope 2008;118:895-901 . 59. Woodworth BA, Lathers D, Neal JG, Skinner M, Richardson M, Young MR, et al. Immunolocalization of surfactant protein A and D in sinonasal mucosa. Am J Rhinol 2006;20:461-5 . 60. Chen PH, Fang SY. The expression of human antimicrobial peptide LL-37 in the human nasal mucosa. Am J Rhinol 2004;18:381-5 . 61. Kim ST, Cha HE, Kim DY, Han GC, Chung YS, Lee YJ, et al. Antimicrobial peptide LL-37 is upregulated in chronic nasal inflammatory disease. Acta Otolaryngol 2003;123:81-5 . 62. Yamasaki K, Schauber J, Coda A, Lin H, Dorschner RA, Schechter NM, et al. Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin. FASEB J 2006;20:2068-80 . 63. Chennupati SK, Chiu AG, Tamashiro E, Banks CA, Cohen MB, Bleier BS, et al. Effects of an LL-37-derived antimicrobial peptide in an animal model of biofilm Pseudomonas sinusitis. Am J Rhinol Allergy 2009;23:46-51 . 64. Golec M. Cathelicidin LL-37: LPS-neutralizing, pleiotropic peptide. Ann Agric Environ Med 2007;14:1-4 . 65. Yim S, Dhawan P, Ragunath C, Christakos S, Diamond G. Induction of catheli- cidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D(3). J Cyst Fibros 2007;6:403-10 . 66. Sultan B, Ramanathan M Jr, Lee J, May L, Lane AP. Sinonasal epithelial cells synthesize active vitamin D, augmenting host innate immune function. Int Forum Allergy Rhinol 2013;3:26-30 . 67. Hansdottir S, Monick MM. Vitamin D effects on lung immunity and respiratory diseases. Vitam Horm 2011;86:217-37 . 68. Akbar NA, Zacharek MA. Vitamin D: immunomodulation of asthma, allergic rhinitis, and chronic rhinosinusitis. Curr Opin Otolaryngol Head Neck Surg 2011;19:224-8 . 69. Mulligan JK, Bleier BS, O’Connell B, Mulligan RM, Wagner C, Schlosser RJ. Vitamin D3 correlates inversely with systemic dendritic cell numbers and bone erosion in chronic rhinosinusitis with nasal polyps and allergic fungal rhinosinusitis. Clin Exp Immunol 2011;164:312-20 . 70. Chen PH, Fang SY. Expression of human beta-defensin 2 in human nasal mucosa. Eur Arch Otorhinolaryngol 2004;261:238-41 . 71. Lee SH, Kim JE, Lim HH, Lee HM, Choi JO. Antimicrobial defensin peptides of the human nasal mucosa. Ann Otol Rhinol Laryngol 2002;111:135-41 . 72. Harder J, Meyer-Hoffert U, Teran LM, Schwichtenberg L, Bartels J, Maune S, et al. Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia. Am J Respir Cell Mol Biol 2000;22:714-21 . 73. Proud D, Sanders SP, Wiehler S. Human rhinovirus infection induces airway epithelial cell production of human beta-defensin 2 both in vitro and in vivo. J Immunol 2004;172:4637-45 . 74. Schutte BC, McCray PB Jr. [beta]-defensins in lung host defense. Annu Rev Physiol 2002;64:709-48 . 75. Vareille M, Kieninger E, Edwards MR, Regamey N. The airway epithelium: soldier in the fight against respiratory viruses. Clin Microbiol Rev 2011;24: 210-29 . 76. Singh PK, Jia HP, Wiles K, Hesselberth J, Liu L, Conway BA, et al. Production of beta-defensins by human airway epithelia. Proc Natl Acad Sci U S A 1998;95: 14961-6 . 77. Tarran R, Grubb BR, Parsons D, Picher M, Hirsh AJ, Davis CW, et al. The CF salt controversy: in vivo observations and therapeutic approaches. Mol Cell 2001;8: 149-58 . 78. Tarran R, Redinbo MR. Mammalian short palate lung and nasal epithelial clone 1 (SPLUNC1) in pH-dependent airway hydration. Int J Biochem Cell Biol 2014;52: 130-5 . 79. Tieu DD, Peters AT, Carter RG, Suh L, Conley DB, Chandra R, et al. Evidence for diminished levels of epithelial psoriasin and calprotectin in chronic rhinosinusitis. J Allergy Clin Immunol 2010;125:667-75 .

26. Zhao KQ, Cowan AT, Lee RJ, Goldstein N, Droguett K, Chen B, et al. Molecular modulation of airway epithelial ciliary response to sneezing. FASEB J 2012;26: 3178-87 . 27. Mall MA, Galietta LJ. Targeting ion channels in cystic fibrosis. J Cyst Fibros 2015;14:561-70 . 28. Illing EA, Woodworth BA. Management of the upper airway in cystic fibrosis. Curr Opin Pulm Med 2014;20:623-31 . 29. Seshadri S, Lu X, Purkey MR, Homma T, Choi AW, Carter R, et al. Increased expression of the epithelial anion transporter pendrin/SLC26A4 in nasal polyps of patients with chronic rhinosinusitis. J Allergy Clin Immunol 2015;136:1548-58 . 30. Ishida A, Ohta N, Suzuki Y, Kakehata S, Okubo K, Ikeda H, et al. Expression of pendrin and periostin in allergic rhinitis and chronic rhinosinusitis. Allergol Int 2012;61:589-95 . 31. Adams KM, Abraham V, Spielman D, Kolls JK, Rubenstein RC, Conner GE, et al. IL-17A induces Pendrin expression and chloride-bicarbonate exchange in human bronchial epithelial cells. PLoS One 2014;9:e103263 . 32. Nofziger C, Dossena S, Suzuki S, Izuhara K, Paulmichl M. Pendrin function in airway epithelia. Cell Physiol Biochem 2011;28:571-8 . 33. Nofziger C, Vezzoli V, Dossena S, Schonherr T, Studnicka J, Nofziger J, et al. STAT6 links IL-4/IL-13 stimulation with pendrin expression in asthma and chronic obstructive pulmonary disease. Clin Pharmacol Ther 2011;90:399-405 . 34. Gudis DA, Cohen NA. Cilia dysfunction. Otolaryngol Clin North Am 2010;43: 461-72, vii . 35. Gudis D, Zhao KQ, Cohen NA. Acquired cilia dysfunction in chronic rhinosinusitis. Am J Rhinol Allergy 2012;26:1-6 . 36. Wilson R, Pitt T, Taylor G, Watson D, MacDermot J, Sykes D, et al. Pyocyanin and 1-hydroxyphenazine produced by Pseudomonas aeruginosa inhibit the beating of human respiratory cilia in vitro. J Clin Invest 1987;79: 221-9 . 37. Zhao KQ, Goldstein N, Yang H, Cowan AT, Chen B, Zheng C, et al. Inherent differences in nasal and tracheal ciliary function in response to Pseudomonas aeruginosa challenge. Am J Rhinol Allergy 2011;25:209-13 . 38. Shen JC, Cope E, Chen B, Leid JG, Cohen NA. Regulation of murine sinonasal cilia function by microbial secreted factors. Int Forum Allergy Rhinol 2012;2: 104-10 . 39. Amitani R, Taylor G, Elezis EN, Llewellyn-Jones C, Mitchell J, Kuze F, et al. Purification and characterization of factors produced by Aspergillus fumigatus which affect human ciliated respiratory epithelium. Infect Immun 1995;63: 3266-71 . 40. Blount A, Zhang S, Chestnut M, Hixon B, Skinner D, Sorscher EJ, et al. Transepithelial ion transport is suppressed in hypoxic sinonasal epithelium. Laryngoscope 2011;121:1929-34 . 41. Shin HW, Cho K, Kim DW, Han DH, Khalmuratova R, Kim SW, et al. Hypoxia-inducible factor 1 mediates nasal polypogenesis by inducing epithelial-to-mesenchymal transition. Am J Respir Crit Care Med 2012;185: 944-54 . 42. Wei CC, Adappa ND, Cohen NA. Use of topical nasal therapies in the management of chronic rhinosinusitis. Laryngoscope 2013;123:2347-59 . 43. Ooi EH, Wormald PJ, Tan LW. Innate immunity in the paranasal sinuses: a review of nasal host defenses. Am J Rhinol 2008;22:13-9 . 44. Ramanathan M Jr, Lane AP. Innate immunity of the sinonasal cavity and its role in chronic rhinosinusitis. Otolaryngol Head Neck Surg 2007;136: 348-56 . 45. Parker D, Prince A. Innate immunity in the respiratory epithelium. Am J Respir Cell Mol Biol 2011;45:189-201 . 46. Persson CG. Plasma exudation in the airways: mechanisms and function. Eur Respir J 1991;4:1268-74 . 47. Klockars M, Reitamo S. Tissue distribution of lysozyme in man. J Histochem Cytochem 1975;23:932-40 . 48. Nash JA, Ballard TN, Weaver TE, Akinbi HT. The peptidoglycan-degrading property of lysozyme is not required for bactericidal activity in vivo. J Immunol 2006;177:519-26 . 49. Prokhorenko IR, Zubova SV, Ivanov AY, Grachev SV. Interaction of gram-negative bacteria with cationic proteins: dependence on the surface characteristics of the bacterial cell. Int J Gen Med 2009;2:33-8 . 50. Woods CM, Hooper DN, Ooi EH, Tan LW, Carney AS. Human lysozyme has fungicidal activity against nasal fungi. Am J Rhinol Allergy 2011;25: 236-40 . 51. Woods CM, Lee VS, Hussey DJ, Irandoust S, Ooi EH, Tan LW, et al. Lysozyme expression is increased in the sinus mucosa of patients with chronic rhinosinusitis. Rhinology 2012;50:147-56 . 52. Tewfik MA, Latterich M, DiFalco MR, Samaha M. Proteomics of nasal mucus in chronic rhinosinusitis. Am J Rhinol 2007;21:680-5 .

10