2018 Section 6 - Laryngology, Voice Disorders, and Bronchoesophalogy

TABLE OF CONTENTS Selected Recent Materials - Reproduced in this Study Guide

2018 SECTION 6: Laryngology, Voice Disorders, and Bronchoesophagology

ADDITIONAL REFERENCE MATERIAL.........................................................................i - iii

I.

Laryngology A. Early glottic cancer

Ahmed J, Ibrahim ASG, Freedman LM, Rosow DE. Oncologic outcomes of KTP laser surgery versus radiation for T1 glottic carcinoma. Laryngoscope . 2018; 128(5):1052- 1056. EBM level 4...........................................................................................................1-5 Summary : This retrospective cohort study compared oncologic outcomes for patients (N = 87) with T1 glottic cancer treated with radiation versus transoral KTP laser resection. Recurrence, laryngeal preservation, disease-free survival, and overall survival rates were statistically similar between the groups. The authors conclude that KTP laser ablation is equivalent to primary radiation therapy in oncologic outcomes for T1 glottic squamous cell carcinoma. Fiz I, Mazzola F, Fiz F, et al. Impact of close and positive margins in transoral laser microsurgery for Tis-T2 glottic cancer. Front Oncol . 2017 Oct 16; doi:10.3389/fonc.2017.00245. [eCollection 2017]. EBM level 4................................6-14 Summary : The authors provide a large series of 507 early glottic cancer patients ranging from carcinoma in situ to T2 and assess the impact of positive margins on disease-specific survival (DSS) and recurrence-free survival. The study indicates that close and positive single superficial margins do not affect DSS. By contrast, all types of margin positivity predict the occurrence of relapses, albeit with different likelihood, depending on stage/margin type. Lee HS, Kim JS, Kim SW, et al. Voice outcome according to surgical extent of transoral laser microsurgery for T1 glottic carcinoma. Laryngoscope . 2016; 126(9):2051-2056. EBM level 4..................................................................................................................15-20 Summary : This article evaluates voice outcomes in a group of patients with T1 glottic carcinoma who underwent transoral laser resection of their tumors. The findings reveal that voice may improve with less advanced types of cordectomy (ELS types I-III) and that voice outcomes are worse with advanced types of cordectomy (IV-V) and when there is anterior commissure involvement.