2018-19 Section 7-Neoplastic and Inflammatory Diseases of the Head and Neck eBook

Research Original Investigation

Survival in Carcinoma of the Minor Salivary Gland

Table. Demographic and Clinicopathologic Characteristics by Histologic Subtype

Subtype, No. (%) of Patients

Adenocarcinoma a (n = 1313)

All (N = 5334)

ACC (n = 1228)

MEC (n = 1568)

Rare (n = 1225)

P Value b

Characteristic

Age, y

18-34 35-44 45-54 55-64 65-74 75-84

620 (11.6) 722 (13.5) 1215 (22.8) 1072 (20.1) 980 (18.4) 556 (10.4)

84 (6.4) 129 (9.8) 267 (20.3) 270 (20.6) 298 (22.7) 200 (15.2)

92 (7.5)

256 (16.3) 237 (15.1) 357 (22.8) 299 (19.1) 248 (15.8) 126 (8.0)

188 (15.3) 192 (15.7) 317 (25.9) 251 (20.5) 194 (15.8)

164 (13.4) 274 (22.3) 252 (20.5) 240 (19.5) 163 (13.3)

<.001

67 (5.5) 16 (1.3)

≥85

169 (3.2)

65 (5.0)

43 (3.5)

45 (2.9)

Sex

Male

2662 (49.9) 2672 (50.1)

614 (46.8) 699 (53.2)

537 (43.7) 691 (56.3)

660 (42.1) 908 (57.9)

851 (69.5) 374 (30.5)

<.001

Female

Race/ethnicity White

3426 (64.2) 451 (8.5) 653 (12.2) 729 (13.7)

895 (68.2) 111 (8.5) 218 (16.6)

831 (67.7) 115 (9.4) 143 (11.6) 125 (10.2)

1107 (70.6) 146 (9.3) 156 (9.9) 132 (8.4) 27 (1.7) 304 (19.4) 256 (16.3) 521 (33.2) 487 (31.1)

593 (48.4)

Hispanic

79 (6.4)

<.001

Black

136 (11.1) 408 (33.3)

Asian or Pacific Islander

64 (4.9) 25 (1.9)

Unknown

75 (1.4)

14 (1.1)

9 (0.7)

Diagnosis year 1988-1994

1030 (19.3) 898 (16.8) 1775 (33.3) 1631 (30.6)

226 (17.2) 235 (17.9) 429 (32.7) 423 (32.2)

269 (21.9) 199 (16.2) 386 (31.4) 374 (30.5)

231 (18.9) 208 (17.0) 439 (35.8) 347 (28.3)

1995-1999 2000-2004 2005-2009

.07

Area SES c No

2464 (46.2) 2869 (53.8)

607 (46.2) 706 (53.8)

552 (45.0) 676 (55.1)

775 (49.4) 792 (50.5)

530 (43.3) 695 (56.7)

Yes

.03

Missing

1 (0.02)

0

0)

1 (0.1)

0

Subsite

Larynx

229 (4.3) 843 (15.8)

58 (4.4)

47 (3.8)

22 (1.4) 89 (5.7)

102 (8.3) 71 (5.8)

Nasal cavity and/or paranasal sinus

287 (21.9)

396 (32.2)

<.001

Oral cavity

3132 (58.7) 1130 (21.2)

852 (64.9) 116 (8.8)

695 (56.6)

1403 (89.5)

182 (14.9) 870 (71.0)

Pharynx

90 (7.3)

54 (3.4)

Surgery None

1337 (25.1) 1112 (20.8) 1502 (28.2)

248 (18.9) 266 (20.3) 422 (32.1) 308 (23.5)

200 (16.3) 449 (36.6) 332 (27.0) 166 (13.5)

141 (9.0) 323 (20.6) 661 (42.2) 382 (24.4)

748 (61.1)

Total

74 (6.0) 87 (7.1)

Partial

<.001

Local tumor destruction 990 (18.6)

134 (10.9) 182 (14.9)

Missing

393 (7.4)

69 (5.3)

81 (6.6)

61 (3.9)

Lymph node examination No

4184 (78.4) 811 (15.2)

1131 (86.1)

1009 (82.2) 171 (13.9)

1263 (80.5) 242 (15.4)

781 (63.8) 284 (23.2) 160 (13.1)

Yes

114 (8.7) 68 (5.2)

<.001

Missing

339 (6.4)

48 (3.9)

63 (4.0)

Radiotherapy No

2628 (49.3) 2604 (48.8)

854 (65.0) 438 (33.4)

385 (31.4) 816 (66.4)

1195 (76.2) 341 (21.7)

194 (15.8) 1009 (82.4)

Yes

<.001

Missing

102 (1.9)

21 (1.6)

27 (2.2)

32 (2.0)

22 (1.8)

Grade d Low e

2103 (59.0) 1464 (41.0)

787 (78.9) 210 (21.1)

183 (62.9) 108 (37.1)

1113 (81.1) 260 (18.9)

20 (2.2)

<.001

High f

886 (97.8)

(continued)

JAMA Otolaryngology–Head & Neck Surgery January 2016 Volume 142, Number 1 (Reprinted)

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