2018-19 Section 7-Neoplastic and Inflammatory Diseases of the Head and Neck eBook
Original Investigation Research
Survival Outcomes With Adjuvant Chemotherapy in Resected Major Salivary Gland Carcinoma
Table 1. Patient and Treatment Characteristics
No. (%) of Patients a RT Alone (n = 1842)
CRT (n = 368)
P Value b
Characteristic
Age, y <65
1000 (54.3) 842 (45.7)
228 (62.0) 140 (38.0)
.007
≥65
Sex
Male
1108 (60.2) 734 (39.8)
264 (71.7) 104 (28.3)
<.001
Female
Race
White
1564 (84.9)
307 (83.4) 39 (10.6)
African American
179 (9.7) 99 (5.4)
.77
Other
22 (6.0)
Insurance status Private
837 (45.4)
202 (54.9)
Medicaid Medicare
83 (4.5)
15 (4.1)
783 (42.5)
127 (34.5)
.045
Other government
26 (1.4) 47 (2.6) 66 (3.6)
5 (1.4) 7 (1.9) 12 (3.3)
Uninsured
Not specified
Median annual income quartile, $ <30 000
77 (4.2)
12 (3.3) 47 (12.8) 55 (14.9) 94 (25.5) 160 (43.5)
30 000-34 999 35 000-45 999
242 (13.1) 327 (17.8) 488 (26.5) 708 (38.4)
.38
≥46 000 Unknown
Residence
Metropolitan
1510 (82.0) 291 (15.8)
310 (84.2) 51 (13.9)
Urban Rural
.58
41 (2.2)
7 (1.9)
Charlson-Deyo comorbidity score c 0
1095 (59.4) 152 (8.3) 31 (1.7) 564 (30.6)
269 (73.1) 45 (12.2) 14 (3.8) 40 (10.9)
1
<.001
≥2
Unknown
Facility type Community cancer program
172 (9.3) 918 (49.8) 751 (40.8)
27 (7.3)
Comprehensive community program Academic or research (includes NCI)
142 (38.6) 199 (54.1)
<.001
Other
1 (0.1)
0
Year of diagnosis 1998-2004
751 (40.8) 1091 (59.2)
155 (42.1) 213 (57.9)
.63
2005-2011
Primary tumor site Parotid gland
1555 (84.4) 227 (12.3)
297 (80.7) 49 (13.3)
Submandibular gland
.005
Sublingual gland Major gland NOS
15 (0.8) 45 (2.4)
1 (0.3) 21 (5.7)
(continued)
90) years; for those undergoing CRT, 62 (range, 18-88) years. Sites ofmost of the included caseswere the parotid gland (1852 [83.8%]), followed by the submandibular gland (276 [12.5%]), any major gland not otherwise specified (66 [3.0%]), and the
in the study; of these, 1842 (83.3%) received RT alone and 368 (16.7%) received CRT ( Figure 1 and Table 1 ). The median fol- low-up for the entire cohort was 39 (range, 2-188)months. The median age of patients undergoing RT alonewas 64 (range, 18-
(Reprinted) JAMA Otolaryngology–Head & Neck Surgery November 2016 Volume 142, Number 11
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