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CONFLICT OF INTEREST The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported. DATA AVAILABILITY STATEMENT The data that support the findings of this study are avail able from the corresponding author upon reasonable request.

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ORCID Andrea Costantino 7785 Bianca Maria Festa 9115 Giuseppe Mercante 7892 Armando De Virgilio

https://orcid.org/0000-0001-5551

https://orcid.org/0000-0003-2060

https://orcid.org/0000-0002-1009

https://orcid.org/0000-0003-0738

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