FLEX November 2023

Patel et al.

Page 16

Author Manuscript Author Manuscript Author Manuscript Author Manuscript (N = 154)

Previous BRAF and MEK adjuvant therapy — no. (%) Yes 3 (2) 1 (1) No 151 (98) 158 (99) Previous radiotherapy — no. (%) Yes 2 (1) 1 (1) No 152 (99) 158 (99) *

Neoadjuvant–Adjuvant Group Adjuvant-Only Group (N = 159) Unknown 51 (33) 57 (36)

Percentages may not total 100 because of rounding. LDH denotes lactate dehydrogenase. † Data were missing in less than 1% of the patients. ‡ Zubrod’s performance ‑ status scores range from 0 to 5, with higher scores indicating greater disability; a score of 0 indicates that the patient is fully active, 1 that the patient is restricted in strenuous activity but is ambulatory, and 2 that the patient is unable to work but is ambulatory and capable of self ‑ care and up and about more than 50% of waking hours. § Stages are defined according to the American Joint Committee on Cancer Cancer Staging Manual , 8th edition.

Characteristic

N Engl J Med . Author manuscript; available in PMC 2023 September 02.