HSC Section 3 - Trauma, Critical Care and Sleep Medicine

Otolaryngology–Head and Neck Surgery

Table 1. Characteristics of Cohort, Protocol, and Voluntary Polysomnogram Patients Followed and Not Followed at 60 Months. a

Month 60 Completed

Month 60 PSG

Original Cohort (N = 126) Yes (n = 97) No (n = 29) P Value b

P Value c

Yes (n = 71)

No (n = 55)

Parameter

Baseline Age

54.5 6 10.2 28.4 6 28.5 32.0 6 11.8 28.9 6 9.6

54.4 6 10.3 55.1 6 10.2 .73 28.6 6 2.5 27.8 6 2.8 .16 30.5 6 10.8 37.2 6 13.5 .01 27.5 6 10.8 33.5 6 14.4 .02 14.7 6 2.9 13.52 6 3.9 .03 11.3 6 5.2 12.4 6 4.0 .33

54.5 6 9.9 28.6 6 2.5 30.4 6 9.4 27.2 6 10.0 14.8 6 2.6 11.6 6 5.0

54.6 6 10.7 .98 28.1 6 2.8 .30 34.1 6 14.1 .09 31.0 6 13.9 .09 13.7 6 3.8 .07 11.5 6 5.0 .86

BMI AHI ODI

FOSQ

14.3 (3.2) 11.6 (5.2)

ESS

Outcomes

Change AHI Month 12

2 16.0 6 16.3 2 17.8 6 18.4 .63 2 19.9 6 12.5 2 13.9 6 17.8 .13

Month 36

Responder

Month 12 Month 18 Month 36

79 (56 of 71) 70 (50 of 71) 80 (53 of 66)

54 (28 of 53) 60 (30 of 50) 65 (20 of 31)

.003

.25 .13

Change FOSQ Month 12

2 2.7 6 2.7 d 2 2.7 6 3.0 d

2 3.2 6 3.6 e 2 2.6 6 4.8 f

2 3.0 6 2.9 2 2.9 6 3.6

2 2.8 6 3.9 .82 2 1.7 6 4.7 .22

.43 .89

Month 36

Change ESS Month 12

5.0 6 5.1 d 4.3 6 5.8 d

4.3 6 4.8 e 4.6 6 5.1 f

4.7 6 5.1 4.0 6 4.9 .53 4.4 6 5.6 4.0 6 4.6 .72

.46 .84

Month 36

Abbreviations: AHI, apnea-hypopnea index; BMI, body mass index; ESS, Epworth Sleepiness Scale; FOSQ, Epworth Sleepiness Scale; ODI, oxygen desaturation index; PSG, polysomnography. a Values are presented as mean 6 SD or % (n). b Complete vs noncomplete. c PSG vs no PSG.

d n = 70. e n = 53. f n = 43.

Table 2. Primary and Secondary Outcomes.

Outcome Measure

Baseline

Month 12

Month 36

Month 60

AHI n

126

124

98

71

Mean 6 SD

32.0 6 11.8

15.3 6 16.1

11.5 6 14.0

12.4 6 16.3

Median

29.3

9.0

6.0

6.2

ODI (4%) n

126

124

98

71

Mean 6 SD

28.9 6 18.2

14.0 6 15.6

9.1 6 11.7

9.9 6 14.5

Median

25.4

7.4

4.8

4.6

FOSQ n

126

123

113

92

Mean 6 SD

14.3 6 3.2

17.3 6 2.9

17.4 6 3.5

18.0 6 2.2

Median

14.6

18.2

18.8

18.7

ESS n

126

123

113

92

Mean 6 SD

11.6 6 5.0

7.0 6 4.3

7.0 6 5.0

6.9 6 4.7

Median

11

6

6

6

Abbreviations: AHI, apnea-hypopnea index; ESS, Epworth Sleepiness Scale; FOSQ, Epworth Sleepiness Scale; ODI, oxygen desaturation index.

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