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Wise et al.

Page 399

Author Manuscript Author Manuscript Author Manuscript Author Manuscript Study design Study groups Clinical endpoint Conclusion

Treatment group had significantly lower nasal and non-nasal symptom scores than the placebo group.

4 nasal and 4 non-nasal symptoms

1 Loratadine-pseudoephedrine; 2 Placebo

Study Year LOE

Grossman et al. 1456 1989 1b RCT (n = 264):

FEV1 = forced expiratory volume in 1 second; HDM = house dust mite; LOE = level of evidence; nPIF = nasal peak inspiratory flow; PFT = pulmonary functiontest; QOL = quality of life; RCT = randomized controlled trial; RQLQ = Rhinoconjunctivitis Quality of Life Questionnaire; SAR = seasonal allergic rhinitis; TSS = Total Symptom score.

Int Forum Allergy Rhinol . Author manuscript; available in PMC 2020 June 10.