xRead - Globus and Chronic Cough (April 2024)

Wamkpah et al.

Page 19

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Fig. 5. Forest plot of the meta-analysis of the proportion of patients with cough improvement for active treatment groups only, stratified by intervention type. The medical therapy category is ordered in clusters by drug class: neuromodulating drugs, tricyclic antidepressants, opioid cough suppressant, inhaled corticosteroids, and combination-drug regimens. Effect sizes (ES) closer to one indicate a higher proportion of patients with cough improvement and are considered to favor treatment. BTX = botulinum toxin; PPI = proton pump inhibitor; VF = vocal fold.

Laryngoscope . Author manuscript; available in PMC 2022 January 01.