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KUANetal.
TABLE X.6 (Continued)
Clinical endpoints 1. Surgical
Study
Year LOE Study design Study groups
Conclusion
Saedi et al. 281
1. EEA for SNM can achieve comparable outcomes to conventional CFR if the tumor is early stage 2. No correlation between surgical approach and the rates of recurrence, complications, and survival 1. EEA had fewer surgical and medical complications, shorter LOS, and better DFS 2. OS is similar between EEA and open approaches EEA outcomes are comparable to the open approach for SNM, but with lower complication rates EEA and open maxillectomy approaches had similar disease recurrence and complications EEA group had lower LOS and operative time EEA was similar to open approach for complication rate, recurrence rate, mortality, operative time, blood loss, and LOS Non-SCC sinonasal cancer managed with EEA has a shorter LOS and similar OS to open approach 1. OS, DSS, negative margins, and rate of intracranial complications were all similar between EEA and combo approaches 2. EEA had descriptively higher rates of CSF leaks EEA and open approaches had comparable 90-day mortality and 5-yearOS Open and EEA had similar proportions of GTR and recurrent disease
2014 3
Retrospective cohort
160 patients EEA( n = 72) Open ( n = 88)
complications
2. Recurrence 3. OS 4. DFS
Suhet al. 280
2013 3
Retrospective cohort
49 patients EEA( n = 36) Open ( n = 13, including
1. Complications 2. DFS 3. OS 4. LOS
endoscopic-assisted approach)
Arnold et al. 297
1. DSS 2. RFS
2012 3
Retrospective cohort
83 patients EEA( n = 28)
3. Margin status 4. Complications 1. Recurrence 2. Complications
Open ( n = 55)
Paridaand Gupta 283
2008 3
Retrospective cohort
28 patients EEA( n = 13) Open ( n = 15) 46 IP patients EEA( n = 10) Open ( n = 36) 34 patients EEA( n = 9)
Kimet al. 287
1. LOS 2. Operative time
2008 3
Retrospective cohort
Batra et al. 314
2005 3
Retrospective cohort
1. Complications 2. Recurrence 3. Mortality 4. Operative time 5. LOS
Open ( n = 25)
1. LOS 2. OS
Povolotskiy et al. 315
1595 patients with
2020 4
Retrospective database (NCDB)
non-SCC sinonasal cancer
EEA( n = 673) Open ( n = 922)
Abdelmeguid et al. 182
2020 4
Retrospective case series
239 patients EEA( n = 167) Endoscopic-assisted combo ( n = 72)
1. OS 2. DSS 3. Margin status 4. Intracranial complications 5. CSF leak
Husain et al. 288
1. 90-day
2292 patients EEA( n = 645) Open ( n = 1647)
2019 4
Retrospective database (NCDB) Retrospective cohort
mortality
2. OS
2014 4 a
Krischek et al. 286
30 patients EEA( n = 9) Open ( n = 16) EEA combined with frontal craniotomy combo ( n = 5)
1. GTR 2. Recurrence 3. Complications
Hanna et al. 289
2009 4 a
1. OS 2. DFS
No difference in OS or DFS between approaches
Retrospective cohort
120 patients EEA( n = 93) Open ( n = 27)
(Continues)
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