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84

KUANetal.

TABLE X.6 (Continued)

Clinical endpoints 1. Surgical

Study

Year LOE Study design Study groups

Conclusion

Saedi et al. 281

1. EEA for SNM can achieve comparable outcomes to conventional CFR if the tumor is early stage 2. No correlation between surgical approach and the rates of recurrence, complications, and survival 1. EEA had fewer surgical and medical complications, shorter LOS, and better DFS 2. OS is similar between EEA and open approaches EEA outcomes are comparable to the open approach for SNM, but with lower complication rates EEA and open maxillectomy approaches had similar disease recurrence and complications EEA group had lower LOS and operative time EEA was similar to open approach for complication rate, recurrence rate, mortality, operative time, blood loss, and LOS Non-SCC sinonasal cancer managed with EEA has a shorter LOS and similar OS to open approach 1. OS, DSS, negative margins, and rate of intracranial complications were all similar between EEA and combo approaches 2. EEA had descriptively higher rates of CSF leaks EEA and open approaches had comparable 90-day mortality and 5-yearOS Open and EEA had similar proportions of GTR and recurrent disease

2014 3

Retrospective cohort

160 patients EEA( n = 72) Open ( n = 88)

complications

2. Recurrence 3. OS 4. DFS

Suhet al. 280

2013 3

Retrospective cohort

49 patients EEA( n = 36) Open ( n = 13, including

1. Complications 2. DFS 3. OS 4. LOS

endoscopic-assisted approach)

Arnold et al. 297

1. DSS 2. RFS

2012 3

Retrospective cohort

83 patients EEA( n = 28)

3. Margin status 4. Complications 1. Recurrence 2. Complications

Open ( n = 55)

Paridaand Gupta 283

2008 3

Retrospective cohort

28 patients EEA( n = 13) Open ( n = 15) 46 IP patients EEA( n = 10) Open ( n = 36) 34 patients EEA( n = 9)

Kimet al. 287

1. LOS 2. Operative time

2008 3

Retrospective cohort

Batra et al. 314

2005 3

Retrospective cohort

1. Complications 2. Recurrence 3. Mortality 4. Operative time 5. LOS

Open ( n = 25)

1. LOS 2. OS

Povolotskiy et al. 315

1595 patients with

2020 4

Retrospective database (NCDB)

non-SCC sinonasal cancer

EEA( n = 673) Open ( n = 922)

Abdelmeguid et al. 182

2020 4

Retrospective case series

239 patients EEA( n = 167) Endoscopic-assisted combo ( n = 72)

1. OS 2. DSS 3. Margin status 4. Intracranial complications 5. CSF leak

Husain et al. 288

1. 90-day

2292 patients EEA( n = 645) Open ( n = 1647)

2019 4

Retrospective database (NCDB) Retrospective cohort

mortality

2. OS

2014 4 a

Krischek et al. 286

30 patients EEA( n = 9) Open ( n = 16) EEA combined with frontal craniotomy combo ( n = 5)

1. GTR 2. Recurrence 3. Complications

Hanna et al. 289

2009 4 a

1. OS 2. DFS

No difference in OS or DFS between approaches

Retrospective cohort

120 patients EEA( n = 93) Open ( n = 27)

(Continues)

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