xRead - Nasal Obstruction (September 2024) Full Articles

20426984, 0, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/alr.23262, Wiley Online Library on [02/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License

109

ICAR SINONASAL TUMORS

TABLE XIII.1 Evidence surrounding diagnostic value of PET in recurrent sinonasal malignancy in previously treated tissue.

Clinical endpoints

Study

Year LOE Study design Study groups

Conclusion

Diagnosis of recurrence at primary site (SN and/or SB) Lamarre et al. 197 2012 3 Retrospective cohort

78 PET/CT analyzed for surveillance

LR

1. To detect local recurrence, negative studies are effective in predicting absence of disease 2. Positive studies need to be viewed cautiously given the high rate of false-positive studies 1. PET/CT is a highly sensitive test for malignant disease 2. The mucosal lining of the reconstructed skull base is a common source for inflammatory pathologies that may lead to false-positive PET/CT PET/CT enables early detection of tumor recurrence and guides endoscopic biopsies in patients with skull base neoplasms The presence of a positive PET/CT 1 month after RT accurately indicated the presence of residual disease in all cases; however, a negative PET indicated absence of disease in only 14% FDG PET–CT seems effective in detecting recurrent/persistent neck disease within the first 2 years of follow-up after nonsurgical treatment of head and neck SCC 1. PET/CT imaging lacks adequate sensitivity and specificity to reliably predict the presence of residual cervical metastatic disease after completion of CRT 2. A negative PET scan appears to be a reliable predictor of the absence of residual tumor (NPV 91.7%)

following surgery or RT ± chemotherapy

Harvey et al. 420

LR

2009 3

Retrospective cohort

34 patients with SB

malignancy treated with surgery, RT, chemotherapy, or a combination

Gil et al. 216

2007 3

Prospective cohort

47 patients with SB malignancy

Recurrence

requiring surgical resection ± RTor CRT with routine posttreatment PET/CT surveillance imaging head and neck SCC treated with RT with postop imaging including CT or MRI and PET 1 month after RT followed by ND afterward treated with CRT followed by postop PET/CT at 3 months and then only when suspicious symptoms or exam advanced head and neck SCC with N + necks treated with CRT and complete response in the primary site with posttreatment PET/CT followed by salvage neck dissection ( n = 21)

Diagnosis of recurrence in previously irradiated neck Rogers et al. 422 2004 4 Prospective case series

12 patients with N +

Persistent

cervical nodal disease

Sagardoy et al. 425

Recurrent/

2016 4

Retrospective case series

43N + SCC patients

persistent cervical nodal disease

Brkovich et al. 424

2006 4

Prospective

19 patients with

Persistent

case series

cervical nodal disease

(Continues)