xRead - Nasal Obstruction (September 2024) Full Articles

20426984, 0, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/alr.23262, Wiley Online Library on [02/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License

344

KUANetal.

TABLE XXXI.B.1 Evidence surrounding baseline QOL in sinonasal malignancies.

Clinical endpoints

Study

Year LOE Study design Study groups

Conclusions

Philips et al. 2103

1. 34% of patients had scores suggestive of borderline depression or anxiety, and 14.8% had scores associated with significant depression or anxiety 2. Worse social support independently predicted lower overall QOL 1. Mean baseline total SNOT-22 score: 37.0 (95% CI: 32.0–42.1) 2. Postoperative SNOT-22 scores: 28.5 (95% CI: 23.4–33.7) at 6 moths, 26.5 (95% CI: 20.4–32.5) at 12 months, and 26.5 (95% CI: 20.8–32.2) at 24 months improvement in all SNOT-22 subdomains at all time points 1. Epistaxis and nasal obstruction were the most common presenting symptoms 2. No patients experienced severe perioperative complications 1. Patients with higher T-stage tumors had worse SNOT-20, ASBQ, and LKE scores than those with lower T-stage tumors 2. Patients with malignant tumors had worse SNOT-20, ASBQ, and LKE scores than those with benign tumors 1. Baseline SNOT-20 score: 1.13 2. Postoperative change in SNOT-20 score: 0 (6 months), –0.22 (1 year), –0.29 (2 years) 3. No statistical change in total SNOT-22 score or rhinologic or ear/face subdomain scores between the preoperative and postoperative time points 4. Statistically significant improvement in SNOT-22 psychological and sleep subdomain scores between the preoperative and 1- and 2-year postoperative time points 7.4% of patients were defined as frail at baseline 3. Statistically significant

1. Posttreatment QOL 2. Predictors of QOL

2020 3

Retrospective cohort

81 patients with SNM who underwent definitive treatment, 87%ofwhom underwent surgery

Glicksman et al. 2093

2018 3

Prospective cohort

82 patients who underwent endoscopic

SNOT-22 scores 1. Baseline 2. Up to 24months after surgery

resection of SNM

Caoet al. 267

1. Baseline

2017 3

Retrospective cohort

33 patients with

symptoms 2. Perioperative complications 1. SNOT-22 2. ASBQ 3. EQ-5D 4. LKE scores

sinonasal mucosal melanoma who underwent resection

Deckard

2015 3

Prospective cohort

71 patients with

et al. 2085

sinonasal and skull base tumors, 39 of whichwere malignant

Derousseau et al. 2090

1. Baseline SNOT-20 score 2. Postoperative

2015 3

Prospective cohort

72 patients with SNM who underwent endoscopic resection

change in SNOT-20 score

Goel et al. 2102

2019 4

Retrospective database study

5346 patients who

Incidence of

underwent resection of SNM

baseline frailty

(National Readmis sions Database)

(Continues)