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and neck. Cancer . 2016;122(23):3632-3640. https://doi.org/10. 1002/cncr.30242 1421. Stelow EB. A review of NUT midline carcinoma. Head Neck Pathol . 2011;5(1):31-35. https://doi.org/10.1007/s12105 010-0235-x 1422. Fang W, French CA, Cameron MJ, Han Y, Liu H. Clinico pathological significance of NUT rearrangements in poorly differentiated malignant tumors of the upper respiratory tract. Int J Surg Pathol . 2013;21(2):102-110. https://doi.org/10.1177/ 1066896912451651 1423. Chau NG, Ma C, Danga K, et al. An anatomical site and genetic-based prognostic model for patients with nuclear protein in testis (NUT) midline carcinoma: analysis of 124 patients. JNCI Cancer Spectr . 2020;4(2):pkz094. https://doi. org/10.1093/jncics/pkz094 1424. Bauer DE, Mitchell CM, Strait KM, et al. Clinicopathologic features and long-term outcomes of NUT midline carcinoma. Clin Cancer Res . 2012;18(20):5773-5779. https://doi.org/10.1158/ 1078-0432.CCR-12-1153 1425. Shakibai N, Contrera KJ, Roberts DB, et al. Sinonasal NUT car cinoma: a consecutive case series. J Neurol Surg B Skull Base . 2022;83(Suppl. 1):S1-S270. Podium presentation at 31st Annual Meeting North American Skull Base Society, Phoenix, Ari zona, USA, February 20, 2022. https://doi.org/10.1055/s-0042 1743754 1426. Arimizu K, Hirano G, Makiyama C, Matsuo M, Sasaguri T, Makiyama A. NUT carcinoma of the nasal cavity that responded to a chemotherapy regimen for Ewing’s sarcoma family of tumors: a case report. BMCCancer . 2018;18(1):1134. https://doi.org/10.1186/s12885-018-5087-x 1427. Piha-Paul SA, Hann CL, French CA, et al. Phase 1 study of molibresib (GSK525762), a bromodomain and extra-terminal domain protein inhibitor, in NUT carcinoma and other solid tumors. JNCI Cancer Spectr . 2020;4(2):pkz093. https://doi. org/10.1093/jncics/pkz093 1428. Morrison-Smith CD, Knox TM, Filic I, et al. Combined target ing of the BRD4-NUT-p300 axis in NUT midline carcinoma by dual selective bromodomain inhibitor, NEO2734. Mol Cancer Ther . 2020;19(7):1406-1414. https://doi.org/10.1158/1535-7163. MCT-20-0087 1429. McLean-Holden A, Ogunbona O, Lubin D, et al. SWI/SNF alterations in poorly-differentiated sinonasal carcinomas: an institutional experience identifying INI1-and BRG1 deficient carcinomas via immunohistochemistry. Lab Invest . 2021;101(Suppl. 1):782-783. 1430. Shah AA, Jain D, Ababneh E, et al. SMARCB1 (INI-1)- deficient adenocarcinoma of the sinonasal tract: a potentially under-recognized form of sinonasal adenocarcinoma with occasional yolk sac tumor-like features. Head Neck Pathol . 2020;14(2):465-472. https://doi.org/10.1007/s12105-019-01065 7 1431. Agaimy A, Hartmann A, Antonescu CR, et al. SMARCB1 (INI 1)-deficient sinonasal carcinoma: a series of 39 cases expand ing the morphologic and clinicopathologic spectrum of a recently described entity. Am J Surg Pathol . 2017;41(4):458-471. https://doi.org/10.1097/PAS.0000000000000797 1432. Kakkar A, Antony VM, Pramanik R, Sakthivel P, Singh CA, Jain D. SMARCB1 (INI1)-deficient sinonasal carcinoma: a series of 13 cases with assessment of histologic patterns. Hum

1407. Kuan EC, Arshi A, Mallen-St Clair J, Tajudeen BA, Abemayor E, St John MA. Significance of tumor stage in sinonasal undif ferentiated carcinoma survival: a population-based analysis. Otolaryngol Head Neck Surg . 2016;154(4):667-673. https://doi. org/10.1177/0194599816629649 1408. Heft Neal ME, Birkeland AC, Bhangale AD, et al. Genetic analysis of sinonasal undifferentiated carcinoma discovers recurrent SWI/SNF alterations and a novel PGAP3-SRPK1 fusion gene. BMC Cancer . 2021;21(1):636. https://doi.org/10. 1186/s12885-021-08370-x 1409. Takahashi Y, Gleber-Netto FO, Bell D, et al. Identification of markers predictive for response to induction chemotherapy in patients with sinonasal undifferentiated carcinoma. Oral Oncol . 2019;97:56-61. https://doi.org/10.1016/j.oraloncology. 2019.07.028 1410. Takahashi Y, Pickering C, Gelbard A, et al. Genomic charac terization of sinonasal undifferentiated carcinoma. J Neurol Surg B Skull Base . 2014;75(Suppl. 1):A084. https://doi.org/10. 1055/s-0034-1370490 1411. Tanzler ED, Morris CG, Orlando CA, Werning JW, Mendenhall WM. Management of sinonasal undif ferentiated carcinoma. Head Neck . 2008;30(5):595-599. https://doi.org/10.1002/hed.20748 1412. Faisal M, Seemann R, Lill C, et al. Elective neck treatment in sinonasal undifferentiated carcinoma: systematic review and meta-analysis. Head Neck . 2020;42(5):1057-1066. https://doi. org/10.1002/hed.26077 1413. Al-Mamgani A, van Rooij P, Mehilal R, Tans L, Levendag PC. Combined-modality treatment improved outcome in sinonasal undifferentiated carcinoma: single-institutional experience of 21 patients and review of the literature. Eur Arch Otorhinolaryngol . 2013;270(1):293-299. https://doi.org/ 10.1007/s00405-012-2008-5 1414. London NR, Mohyeldin A, Daoud G, et al. Sinonasal undif ferentiated carcinoma: institutional trend toward induc tion chemotherapy followed by definitive chemoradiation. Head Neck . 2020;42(11):3197-3205. https://doi.org/10.1002/ hed.26357 1415. Lehrich BM, Goshtasbi K, Abiri A, et al. Impact of induc tion chemotherapy and socioeconomics on sinonasal undif ferentiated carcinoma survival. Int Forum Allergy Rhinol . 2020;10(5):679-688. https://doi.org/10.1002/alr.22536 1416. Fu TS, Chin CJ, Xu W, et al. Neoadjuvant radiation improves margin status compared to adjuvant radiation among patients with non-squamous cell carcinoma sinonasal malignancies. J Neurol Surg B Skull Base . 2016;77(Suppl. 1):A088. https://doi. org/10.1055/s-0036-1579876 1417. Hafstrom A, Sjovall J, Persson SS, Svensson C, Brun E, Greiff L. Outcome for sinonasal malignancies: a population based survey. Eur Arch Otorhinolaryngol . 2022;279(5):2611 2622. https://doi.org/10.1007/s00405-021-07057-0 1418. Bishop JA, Westra WH. NUT midline carcinoma of the sinonasal tract. Am J Surg Pathol . 2012;36(8):1216-1221. https:// doi.org/10.1097/PAS.0b013e318254ce54 1419. French CA. NUT carcinoma: clinicopathologic features, pathogenesis, and treatment. Pathol Int . 2018;68(11):583-595. https://doi.org/10.1111/pin.12727 1420. Chau NG, Hurwitz S, Mitchell CM, et al. Intensive treatment and survival outcomes in NUT midline carcinoma of the head