xRead - Nasal Obstruction (September 2024) Full Articles
20426984, 2021, 3, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/alr.22741 by Stanford University, Wiley Online Library on [01/07/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
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International consensus statement on rhinosinusitis
uncomplicated pediatric ARS. If > 10days or complicated,
Strong Recommendation: Consider use in ARS
Recommendation: Antibiotics should not be given for the first 10 days of
amoxicillin-clavulanate is
preferred antibiotic if not allergic
Option: Saline irrigation may be used in adjunct with antibiotics for acute
bacterial rhinosinusitis.
Option: Consider watchful waiting in uncomplicated
cases with institution after 7 days or with worsening/ mitigating circumstances
Benefit-Harm Assessment Policy Level
Low Benefit over placebo small but tangible
outweigh harms and costs
Low Balance of benefit and harm
Benefit over placebo is small
None Benefits likely
Moderate
TABLE I-3 Grade A/B evidence-based recommendations for medical management of ARS Intervention Grade Benefit Harm Cost ARS: Antibiotic Treatment B Shorter symptom duration, reduced pathogen carriage GI complaints, resistance, anaphylaxis; See Table II-1. Lowto Pediatric ARS < 10 days: Withholding Antibiotic Treatment A Avoidance of unnecessary medications Potential progression of disease ARS: Intranasal Corticosteroids A Improved symptoms as Minimal harm with rare adverse events; See Table II-1.
Unclear but possible ear fullness, or
irritation; See Table II-1.
monotherapy in mild to moderate cases and as
adjuvant to antibiotics in severe cases. May shorten recovery
B No benefit to 10 cc syringe but possible improvement in
patency, rhinorrhea,
and post-nasal drip with high volume irrigation
ARS: Topical Saline Sprayand Irrigation
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