xRead - Nasal Obstruction (September 2024) Full Articles

20426984, 2021, 3, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/alr.22741 by Stanford University, Wiley Online Library on [01/07/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License

232

International consensus statement on rhinosinusitis

Recommendation against Mitomycin C

evidence does exist

suggesting packing may reduce adhesion

formation, it is limited and has not been

compared to studies

employing early and

frequent debridement

Corticosteroid-eluting

stents can be considered in the postoperative

ethmoidectomy cavity

Option for systemic corticosteroids

Option. Although

Option.

Benefit-Harm Assessment Policy Level

Balance of risks and benefits

benefit over harm

Moderate to high Balance of benefit and harm

Minimal Balance of benefit and harm

Preponderance of

Costs associated withall packing

materials.

Absorbable

materials are

more costly than

nonabsorbable packing

depending on stents and

medication

Variable

Intervention Grade Benefit Harm Cost Systemic

Potential for increased discomfort insitu and on removal.

Rare risk of toxic

shock syndrome. Potential for an

increased rate of

adhesions with

some materials

Off-label use, systemic absorption, local toxicity

misplacement and local reaction

Insomnia, mood changes,

hyperglycemia,

gastritis, increased intraocular

pressure, avascular necrosis

Potential for

A Potential reduction in post-operative adhesion and

improved ostial size

with some materials

polyposis and

adhesions which

translates into a reduction in

postoperative

interventions

Mitomycin C B Reduction in synechia formation, improvement in

maxillary ostium patency

C Improvement in endoscopic

appearance,

reduction in polyp recurrence.

A Reduction in

TABLE I-8 (Continued)

Post-operative Packing

Corticosteroids

Drug-eluting Implants

Post-operative