xRead - Nasal Obstruction (September 2024) Full Articles

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Orlandi et al.

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obstruction in addition to presence of facial pain/pressure or hyposmia. Lanza 523 2004 2 Review CRS patients Diagnostic criteria for CRS CRS defined as presence of 2 + major or 1 major&2 + minor for 12 consecutive

Single most important finding is presence of purulence in nasal cavity or posterior oropharynx. Benninger 143 2003 2 Review CRS patients Multidisciplinary task force formed to develop definitions for CRS Duration of disease > 12 consecutive weeks or > 12 weeks of physical findings Presence of 1 + signs of inflammation: ∙ Discolored nasal drainage

CRS is defined as presence of at least 2 symptoms for > 12 weeks, one of which must be nasal discharge or nasal

∙ Edema/erythema middle meatus ∙ Generalized or localized edema (if not involving bulla or middle meatus, imaging required)

weeks with objective evidence that disease is present.

Imaging modality confirming diagnosis Sensitivity of self-reporting for CRS was 84% and specificity 82%

Symptoms from IHS for primary headache can differentiate CRS

patients from non-CRS patients with CRS-symptoms. Hyposmia is positively predictive for CRS while facial

pain/headache are negatively predictive

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Thomas 530 2008 2 Clinical Practice Guidelines

Workman 527 2019 3 Prospective cohort study Adults with RS Evaluate the value of self-reporting

questionnaires on

diagnostic assessment of CRS

CRSwNP Evidence-based methodology to identify and grade recommendations for management of RS

Symptoms from Task Force on Rhinosinusitis and

International Headache Society criteria

Adults with CRS

Adults without CRS

Hsueh 525 2013 3 Retrospective cohort study

TABLE IX-1 (Continued)