xRead - Nasal Obstruction (September 2024) Full Articles

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TABLE IX-2 Evidence for the cost-effective diagnosis of CRS Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Symptom-Based Criteria Amine 546 2013 3 Cohort study Patients with 2 or more CRS-associated symptoms Patients with 1 CRS-associated symptom Diagnosis of CRS based on CT imaging or endoscopy Patients with more CRS symptoms had a higher liklihood of CRS diagnoses confirmed by CT. Nasal obstruction was the most sensitive, while hyposmia was the least sensitive Presenting patient

only presenting symptom

positively associated with positive scan results.

Hyposmia was more common symptom indicative of CT-confirmed CRS.

Headaches, facial pain, and sleep disturbances were

more significant in patients without radiographic confirmation.

The prevalence of CRS was 60% in patients complaining of

CRS-associated symptoms, with chronic purulent

rhinorrhea and hyposmia individually and in

combination as significant predictors of CRS diagnosis.

Nasal obstruction was the

Lund-Mackay grading of CT scans

symptomatology and comorbid illnesses

Abrass 551 2011 3 Cohort study Patients with active CRS symptoms but negative endoscopy

and radiographic evidence ofCRS

CRS-associated symptoms without radiographic evidence of CRS

Pynnonen 514 2007 3 Cohort study Patient presenting for evaluation of

CRS-associated symptoms

Ferguson 550 2012 3 Cohort study CRS-associated symptoms