xRead - Nasal Obstruction (September 2024) Full Articles

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393

Orlandi et al.

(Continues)

Culig 1056 2010 3 RCT,UB Hypertonic seawater (30) Isotonic seawater (30) Spray Symptoms All symptoms improved in the group of patients using hypertonic

While only congestion and rhinorrhea improved in the

group of isotonic

seawater solution.

Warming saline is not necessary and adds no additional benefit to

room-temperature saline irrigation.

No difference between Ems salt hypertonic solution and

isotonic irrigation at 7days.

irrigation is more effective than

isotonic saline in

symptoms reduction and patient satisfaction.

MCC Mucociliary clearance improved after irrigation with

hypertonic saline

but did not with

isotonic saline.

Study Year LOE Study Design Study Groups (N) Device Clinical Endpoint Conclusions Symptoms Endoscopy MCC

seawater solution.

Hypertonic saline

Olfactometry Radiology MCC

PNIF

Nasal resistance Nasal volume Symptoms

Adverse event

Drop Symptoms

Nasal airflow

Patient satisfaction

200 mL irrigation (nasal irrigator)

irrigation

(syringe)

250 mL irrigation (squeeze bottle)

4mL/side

Nimsakul 1057 2018 3 RCT, SB Heated isotonic saline (12)

isotonic saline (11)

Bachmann 1060 2000 2 RCT,DB Ems salt hypertonic solution (20)

Berjis 1055 2011 3 RCT,UB Hypertonic saline (57) Isotonic saline (57)

Room-temperature

Healthy control (9)

Isotonic saline (20)

Ural 1054 2009 3 RCT, SB Hypertonic saline (18) Isotonic saline (24)

TABLE IX-25 (Continued)