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International consensus statement on rhinosinusitis
Symptomatic relief and reduction in eosinophil count in the blood were observed; decoction of
KatuwelbatuDeduruKatukadiya can be used in treatment of CRS.
Efficacy similar to macrolides for CRSwNP. A placebo effect possible in both treatment groups.
Herbal dry extract BNO 1011 improves radiographic, histologic, and MCC
parameters in a rabbit model of CRS.
TABLE IX-39 Evidence for CRS management with herbal medications Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Anushiravani 1213 2018 2 Systematic analysis 936 articles selected 4 eligible for review Study and define the effects of medicinal plants on CRS All included articles showed the effectiveness of the medicinal plants in the treatment of CRS. Because of several biases, the Ediriweera 1214 2010 3 Randomized clinical trial 80 patients. Group A (40) treatment, Group B (40) Placebo Evaluate the efficacy of this decoction in Efficacy of
effectiveness of medicinal plants needs to be further proven through additional studies.
Symptoms relieved. Only 10% of patients unchanged or aggravated. Traditional
decoction PitawakkaNavaya is beneficial forCRS.
May be an effective treatment for CRSwNP but needs further investigation.
maxillary epithelial Cl − secretion, airway surface liquid and
Kaphaja Shira Shula in CRS
Efficacy of Chinese herbal medicine in the treatment of CRSwNP in comparison with
erythromycin treatment for 8weeks Effectiveness of a Pimpinella
on: sinus opacification
submucosal gland densityon
histopathology.
PitawakkaNavaya in treatment of CRS
anisum–based herbal
medicine for treating
CRSwNP in comparison to fluticasone nasal spray
Effectiveness evaluated
48 patients: first group (n = 26) P.
(n = 10), Group 2
BNO low dose (n = 10), Group 3
BNO high dose (n = 10)
(n = 22) fluticasone nasal spray
Tsang-Erh-San
extract granules
and Houttuynia
extract powder 27 erythromycin
Zealand white
rabbits: Group 1 oral placebo
60 patients. Group A (30) treatment, Group B (30) Placebo
anisum–based
herbal medicine second group
53 patients: 26
CRS in 30 New
clinical trial
Cho 915 2019 5 Trial on animal model
Maragalawaththa 1215 2010 3 Randomized clinical trial
clinical trial
Vazifehkah 1216 2016 3 Randomized
Jiang 1112 2012 3 Randomized
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