xRead - Nasal Obstruction (September 2024) Full Articles

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485

Orlandi et al.

Isolated low IgG subclass had limited value in patient assessment. C4A null

alleles are associated with CRS and RARS.

Incidence R-CRS associated with low pre-immunization

anti-pneumococcal titer and specific antibody

deficiency. No difference with CRSwNP. Cui 804 2009 4 Case-control study CRSwNP (n = 95) CRSsNP (n = 72)

A link between IgG subclass deficiency and CRSwNP seems unlikely.

deficiency is not the main cause of CRS in adult Chinese patients.

Baraniuk 1515 2005 4 Retrospective case series 99 CRS (50% with CRSwNP) Incidence Ig subclass deficiencies were more prevalent in CRSsNP than CRSwNP.

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Tran Khai Hoan 1514 2014 4 Prospective case series Operated (n = 118)

Ig, C3, C4, and MBL

Ig and IgG subclass level, plasma C3, C4 level, C4 immune typing

levels, symptom scale, endoscopy

Ig and IgG subclass level, plasma C3, C4 level, MBL

Ig and IgG subclass

Unselected control (n = 150) Healthy control (n = 48)

Healthy control (n = 110)

Not operated (n = 43)

Seppanen 937 2006 4 Case-control study R-CRS (n = 48) ARS (n = 50)

129 CRS (42% with CRSwNP)

Carr 943 2011 4 Retrospective case series

TABLE X-15 (Continued)