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549

Orlandi et al.

Controlled hypotension MAP > 55 maintained cerebral oxygenation

Ankichetty 1843 2011 2 RCT, double blind Controlled hypotension in higher LMS improved visualization Ragab 1844 2010 2 RCT IA(n = 35) TIVA(n = 35) Heart rate IA(n = 40) TIVA(n = 40) Time to optimal MAP EBL Operative time Surgical visualization (Boezaart)

Yoo 1831 2010 2 RCT, No significant differences in surgical visualization with controlled hypotension MAP65 Wormald 1847 2005 2 RCT TIVA(n = 28) IA(n = 28) MAP Heart rate EBL Eberhart 1850 2003 2 RCT, TIVA(n = 45) IA(n = 43) MAP double-blind TIVA(n = 20) IA w/ sevoflurane (n = 20) IA w/ desflurane (n = 20) Surgical visualization (Boezaart) Heart rate MAP

TIVA improved surgical visualization, particularly in patients with high LMS

Controlled hypotension improved visualization with TIVA.

Controlled hypotension improved visualization with TIVA

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Cho 1841 2012 2 RCT, single blind IA(n = 32) TIVA(n = 36) Operative time

Controlled hypotension MAP 50-60 TIVA better visualization

Surgical visualization (Fromme)

Surgical visualization (VAS) Heart rate EBL

Surgical visualization (VAS and Boezaart)

Surgical visualization (Boezaart) Heart rate EBL

5) Complication rate Blood pressure

n = 41 MAP

Mean arterial pressure Heart rate

Change in hemoglobin Surgical visualization

Operative time EBL

Cerebral oxygenation

double-blind

observational trial

Farzanegan 1855 2018 3 Prospective

TABLE XII-2 (Continued)

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