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560
International consensus statement on rhinosinusitis
TABLE XII-5 Evidence for appropriate medical therapy prior to surgery
Systemic corticosteroids
Guideline
Antibiotics
INCS
Saline Irrigation Other
Not specified
Oral or topical
AAOA Guidelines 2009 526
Yes
Yes
Yes for CRSwNP or CRSsNP if initial 2 week treatment fails
decongestants
AAO-HNS
Yes – culture directed
Optional
Optional
Optional
Treatment of AR
Guidelines 2015 88
BSACI 2008 1921
Yes
Leukotrienes optional in AERD patients; Antihistamines for AR Leukotrienes optional in AERD patients
macrolide
Yes
Yes in mod/severe CRSwNP; No for CRSsNP Yes in CRSwNP; Optional in CRSsNP
antibiotics
Canadian
Yes – culture directed
Yes
Optional
Guidelines 2011 151
EPOS2020 26
Yes
Optional
Yes
Optional long term macrolides for CRSsNP
TABLE XII-6 Results of surveys to establish medical therapy trial prescribing habits prior to surgery
Systemic corticosteroids
Survey
Antibiotics
INCS
Saline Irrigation Other
AAOHNS Survey 2006, n = 80 1197 ARS Survey, 2007 n = 308 1922 Chinese Oto-HNS Alliance Survey, 2020 n = 134 1923 ENTUK Survey, 2013, n = 159 1924
94%
94%
34%
47% oral decongestants 47% mucolytics
51% always, 30% almost always 19% always, 34% often
10% always, 20% almost always
51% always, 40% often
3% always, 12% often 35% always, 45% often
92%
61% always, 27% sometimes
4% always, 30% sometimes
23% always, 42% sometimes
3% antihistamines 4%topical decongestants
TABLE XII-7 Duration of medical therapy trials prior to surgery recommended by major guidelines
Systemic corticosteroids
Guideline
Antibiotics
INCS
Saline Irrigation
3-4weeks
At least 1 month
8-12days
Not specified
AAOA Guidelines 2009 526
AAO-HNS
2-4weeks
Not specified
Not specified
Not specified
Guidelines 2015 88
"Slightly longer
Not specified
2 weeks in CRSwNP; Optional in CRSsNP
Not specified
Canadian
than for ABRS"
Guidelines 2011 151
EPOS2020 26 BSACI 2007 1921
Not explicitly stated
6-12weeks
1-3weeks 5-10days
6-12weeks
Not specified
Yes
12weeks of
macrolide antibiotics
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