xRead - Nasal Obstruction (September 2024) Full Articles

20426984, 2021, 3, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/alr.22741 by Stanford University, Wiley Online Library on [01/07/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License

614

International consensus statement on rhinosinusitis

compared to Merocel R

(Continues)

Significant improvement in ostial size for Chitogel alone and Chitogel + budesonide

Grzeskowiak 2203 2018 2 DBRCT 80 patients 160 sides Nasopore + saline vs nasopore + steroid vs nasopore + antibiotic Healing and secretions Steroid + nasopore had improved healing and less secretions Shi 2193 2013 2 RCT PureRegen R gel plus Merocel R vsMerocel R alone PureRegen R gel had better%

re-epithelization, Incidence of

non-obstructing

adhesions, edema, and crusting

Garzaro 2200 2020 2 RCT Gloved PVA pack vs PVA pack + lidocaine Yayik 2199 2019 2 RCT Lidocaine soaked pack vs lidocaine + dexamethasone soaked pack Pain post surgery Less pain in first 24 hours post surgery Ngoc 2188 2013 2 Single surgeon DBRCT Pain in 24 hours post surgery Gloved PVA pack had less pain 72 patient – 144 sides

compared to no packing

Higher adhesion rate for ungloved pack Significantly better

endoscopic score at 4

weeks but no difference later

No significant difference in wound healing.

Significantly larger ostial sizes for CD treated cavities

No significant difference for infection, adhesions or frontal ostial size;

fibrin sealant showed

less granulation tissue at 2 and 4 weeks and less crusting a 1 week

Author Year LOE Study Design Materials Outcome Measure Findings Yu 2174 2014 2 Nonblinded RCT

CD gel (Chitogel R ) vs no packing Wound healing including adhesion rate

Ostial size at 3 months for maxillary, frontal and sphenoid

Endoscopic findings of crusting, infection, adhesions, frontal

stenosis, granulation tissue

Wound healing including adhesion rate

Ostial size at 3, 6, 12 months for maxillary, frontal and sphenoid

Lund-Kennedy

endoscopic score

adhesions, edema, and crusting.

Gloved Merocel R vsMerocel R Adhesion rate Postoperative

Re-epithelialization,

+

CD gel (Chitogel R ) vs Chitogel

Aerosolized fibrin sealant vs Merocel R

budesonide vs no packing vs betamethasone cream

Ha 2189 2018 2 Single surgeon DBRCT

41 patients – 82 sides

36 patients – 72 sides

54 patients – 108 sides

Kim 2178 2012 2 RCT

15 patients – 30 sides

26 patients – 52 sides

TABLE XII-21 (Continued)