xRead - Nasal Obstruction (September 2024) Full Articles

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Orlandi et al.

Significant improvement in ostial size for Chitogel R aloneand Chitogel R + budesonide compared to no packing (Continues)

Healing and secretions Steroid + nasopore had improved

TABLE XII-24 Evidence for use of drug eluting stents with sinus surgery Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Smith 2020 1 Evidence based review with recommendations Review of steroid-eluting sinus stents Included all RCTs of steroid-eluting sinus stents 31 studies evaluated; concludes a recommendation for their use to be considered in carefully selected patients. Huang 2248 2015 1 Cochrane database of systemic reviews Review of steroid-eluting sinus stents Included all RCTs comparing steroid-eluting sinus stents with non-steroid-eluting No RCTs that met inclusion criteria largely due to within-patient comparison. Conclusion that

sinus stents, nasal packing or no treatment – 21 trials with potential identified there currently is no evidence of benefit in high-quality RCTs over no packing or nasal packing Han 1611 2012 1 Meta-analysis 2 RCTs of outcomes at postoperative day 30. MT lateralization Adhesions Frank polyposis

Merocel in finger cot had less adhesions and better SNOT 22 scores at day 20 but differences disappeared after that time point healing and less secretions

Relative reduction of adhesions and polyposis. 35% reduction in postoperative intervention.

40% reduction in oral corticosteroid usage.

Wound healing including adhesion rate

Ostial size at 3, 6 12 months for maxillary, frontal and sphenoid

Need for postoperative intervention

Need for postoperative corticosteroids

Propel vs merocel in finger cot Adhesions Lund Kennedy Snot 22 Nasopore + salinevs nasopore + steroidvs nasopore + antibiotic

CD gel (Chitogel R ) vs Chitogel R + budesonide vs

no packing vs

betamethasone cream

2020 2 RCT

40 patients – 80 sides

Ha 2189 2018 2 Single surgeon DBRCT 36 patients – 72 sides

Grzeskowiak 2203 2019 2 DBRCT 80 patients 160 sides

Rawl

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