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638

International consensus statement on rhinosinusitis

19.2%). Adenoiditis alone was High IgE in 2/10 and non-protective, S. pneumonia

Children with positive skin tests had 1.09 more sinus infections than children with negative skin tests ( p < 0.012)

confirmed ARS compared to

4.6% in the control group. The

difference was not significant.

titers in 4/10 patients with RARS.

patients with a clinical history

of AR in the CRS group (90.2%) vs the ARS group (74.8%).

Percentage of positive skin prick tests similar in both groups.

diagnosis was associated with a significantly higher incidence rate of ARS.

patients (isolated in 80.8% and coupled with adenoiditis in

confirmed in 7% of the cohort.

Most common predisposing factor was IgG subclass

deficiency (78.7%), non-allergic rhinitis (64.9%) and allergic rhinitis (35.1%).

TABLE XIII-1 Risk factors for pediatric ARS Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Lin 351 2019 3 Retrospective cohort study between 2000 and2012 Children with newly diagnosed allergic rhinitis (n = 23,046),

7% of allergic children had

Statistically significantly more

Having an allergic rhinitis

ARS confirmed in 89.2% of the

ARS prevalence during the allergy season

abnormalities on clinical testing

Clinical history of AR and percentage with positive skin prick tests

Incidence rate of ARS determined by diagnostic codes

adenoiditis made by nasal endoscopy

94 children with RARS. Reviewed clinical characteristics of the children

Occurrence of acute sinus infections

Immunologic

Diagnosis of ARS or

Children with allergic sensitization to grass pollen and rhinitis symptoms (n = 242),

and a matched cohort without an allergy diagnosis (n = 23,046)

Children with a diagnosis ofCRS (n = 17) orRARS (n = 10) between 2008-18

and children without inhalant allergies (n = 65)

Children with either ARS orCRS

287 consecutive children in whom ARS was suspected based on symptoms

positive or negative skin tests to inhalant allergens

Children with either

Leo 357 2018 3 Prospective cohort study

Li 2301 2020 4 Retrospective pilot study

collected cohort

Marseglia 2300 2007 3 Cross sectional study

record review

Furukawa 2299 1992 4 Retrospective review

Veskitkul 489 2015 4 Retrospective

Poachanukoon 223 2012 4 Prospectively