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International consensus statement on rhinosinusitis

1498. Dogan M, Sahin M, Yenisey C. Increased TSLP, IL-33, IL 25, IL-19, IL 21 and amphiregulin (AREG) levels in chronic rhinosinusitis with nasal polyp. Eur Arch Otorhinolaryngol . 2019;276(6):1685-1691. 1499. Ogasawara N, Klingler AI, Tan BK, et al. Epithelial activa tors of type 2 inflammation: elevation of thymic stromal lym phopoietin, but not IL-25 or IL-33, in chronic rhinosinusitis with nasal polyps in Chicago, Illinois. Allergy . 2018;73(11):2251 2254. 1500. Liao B, Cao PP, Zeng M, et al. Interaction of thymic stro mal lymphopoietin, IL-33, and their receptors in epithelial cells in eosinophilic chronic rhinosinusitis with nasal polyps. Allergy .70(9):1169-1180. 1501. Miljkovic D, Bassiouni A, Cooksley C, et al. Associa tion between Group 2 Innate Lymphoid Cells enrichment, nasal polyps and allergy in Chronic Rhinosinusitis. Allergy . 2014;69(9):1154-1161. 1502. Song W, Wang C, Zhou J, Pan S, Lin S. IL-33 expression in chronic rhinosinusitis with nasal polyps and its relation ship with clinical severity. ORL J Otorhinolaryngol Relat Spec . 2017;79(6):323-330. 1503. Kouzaki H, Matsumoto K, Kato T, Tojima I, Shimizu S, Shimizu T. Epithelial cell-derived cytokines contribute to the pathophysiology of eosinophilic chronic rhinosinusitis. J Interferon Cytokine Res . 2016;36(3):169-79. 1504. Endo Y, Hirahara K, Iinuma T, et al. The interleukin-33-p38 Kinase axis confers memory T helper 2 cell pathogenicity in the airway. Immunity . 2015;42(2):294-308. 1505. Stevens WW, Ocampo CJ, Berdnikovs S, et al. Cytokines in chronic rhinosinusitis: role in eosinophilia and aspirin exacerbated respiratory disease. Am J Respir Crit Care Med . 2015;192(6):682-694. 1506. Baba S, Kondo K, Kanaya K, et al. Expression of IL-33 and its receptor ST2 in chronic rhinosinusitis with nasal polyps. Laryngoscope . 2014;124(4):E115-E122. 1507. Paris G. Damage-associated molecular patterns stimulate interleukin-33 expression in nasal polyp epithelial cells. Int Forum Allergy Rhinol . 2014;4(1):15-21. 1508. Shaw JL FS, Citardi MJ, Porter PC, et al.. IL-33–Responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps. Am J Respir Crit Care Med . 2013;188(4):432-439. 1509. Peng Y, Zi XX, Tian TF, et al. Whole-transcriptome sequenc ing reveals heightened inflammation and defective host defence responses in chronic rhinosinusitis with nasal polyps. Eur Respir J . 2019;54(5):1900732. 1510. Czerny MS, Namin A, Gratton MA, Antisdel JL. Histopatho logical and clinical analysis of chronic rhinosinusitis by sub type. Int Forum Allergy Rhinol . 2014;4(6):463-469. 1511. Braverman I, Wright ED, Wang CG, Eidelman D, Frenkiel S. Human nasal ciliary-beat frequency in normal and chronic sinusitis subjects. J Otolaryngol . 1998;27(3):145-152. 1512. Peng Y, Guan WJ, Tan KS, et al. Aberrant localization of FOXJ1 correlates with the disease severity and comorbidities in patients with nasal polyps. Allergy Asthma Clin Immunol . 2018;14:71. 1513. Schwitzguébel AJ-P, Jandus P, Lacroix J-S, Seebach JD, Harr T. Immunoglobulin deficiency in patients with chronic rhi-

1481. Salman S, Akpinar ME, Yigit O, Gormus U. Surfactant protein A and D in chronic rhinosinusitis with nasal polyposis and corticosteroid response. Am J Rhinol Allergy . 2012;26(2):e76 e80. 1482. Park SK, Heo KW, Hur DY, Yang YI. Chitinolytic activity in nasal polyps. Am J Rhinol Allergy . 2011;25(1):12-14. 1483. Wang X, Zhao C, Liu M. Expression and significance of sur factant A in nasal polyps of chronic rhinosinusitis. LinChung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi . 2010;24(14):652-654. 1484. Ramanathan M, Jr., Lee WK, Spannhake EW, Lane AP. Th2 cytokines associated with chronic rhinosinusitis with polyps down-regulate the antimicrobial immune function of human sinonasal epithelial cells. AmJRhinol . 2008;22(2):115-121. 1485. Ramanathan M, Jr., Lee WK, Dubin MG, Lin S, Spannhake EW, Lane AP. Sinonasal epithelial cell expression of toll-like receptor 9 is decreased in chronic rhinosinusitis with polyps. AmJRhinol . 2007;21(1):110-116. 1486. Claeys S, Van Hoecke H, Holtappels G, et al. Nasal polyps in patients with and without cystic fibrosis: a differentiation by innate markers and inflammatory mediators. Clin Exp Allergy . 2005;35(4):467-472. 1487. Chen PH, Fang SY. The expression of human antimicrobial peptide LL-37 in the human nasal mucosa. Am J Rhinol . 2004;18(6):381-385. 1488. Schicht M, Knipping S, Hirt R, et al. Detection of surfactant proteins A, B, C, and D in human nasal mucosa and their regulation in chronic rhinosinusitis with polyps. AmJRhinol Allergy . 2013;27(1):24-29. 1489. Claeys S, de Belder T, Holtappels G, et al. Human beta defensins and toll-like receptors in the upper airway. Allergy . 2003;58(8):748-753. 1490. Mansson A, Bogefors J, Cervin A, Uddman R, Cardell LO. NOD-like receptors in the human upper airways: a potential role in nasal polyposis. Allergy . 2011;66(5):621-628. 1491. Zhao CY, Wang X, Liu M, Jin DJ. Microarray gene analysis of Toll-like receptor signaling elements in chronic rhinosinusitis with nasal polyps. Int Arch Allergy Immunol . 2011;156(3):297 304. 1492. Xia Z, Kong W, Yue J, Wang Y, Wu L. Effects of toll-like receptor-9 expression in chronic rhinosinusitis with nasal polyps. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi . 2008;22(14):631-633. 1493. Lane AP, Truong-Tran QA, Schleimer RP. Altered expres sion of genes associated with innate immunity and inflamma tion in recalcitrant rhinosinusitis with polyps. Am J Rhinol . 2006;20(2):138-144. 1494. Ramanathan M, Jr., Lee WK, Lane AP. Increased expression of acidic mammalian chitinase in chronic rhinosinusitis with nasal polyps. AmJRhinol . 2006;20(3):330-335. 1495. Cao Y, Chen F, Sun Y, et al. LL-37 promotes neutrophil extra cellular trap formation in chronic rhinosinusitis with nasal polyps. Clin Exp Allergy . 2019;49(7):990-999. 1496. Zhai GT, Wang H, Li JX, et al. IgD-activated mast cells induce IgE synthesis in B cells in nasal polyps. J Allergy Clin Immunol . 2018;142(5):1489-1499.e1423. 1497. Baba S, Kondo K, Suzukawa M, Ohta K, Yamasoba T. Distri bution, subtype population, and IgE positivity of mast cells in chronic rhinosinusitis with nasal polyps. Ann Allergy Asthma Immunol . 2017;119(2):120-128.