xRead - Olfactory Disorders (September 2023)

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470

INTERNATIONAL CONSENSUS ON OLFACTION

TABLE VII.16b (Continued)

Olfactory test method used

Author

Year

LOE Study design Study groups

Conclusions

SS-TDI

Odor identification function was lower in patients with AN compared with controls function was higher in patients with AN compared with controls Patients with AN had higher odor discrimination but lower threshold function compared with controls higher in patients with AN compared with controls higher in patients with AN compared with controls Patients with AN had higher olfactory sensitivity compared with controls No relevant difference in OF between the Odor identification Overall OF was Overall OF was No relevant difference in OF between the AN and control groups The findings indicate alterations of smell capacity in patients withAN Olfaction was largely intact in patients with AN compared with controls low weight and control groups

Patients with AN (n = 19) Controls (n = 21, allwomen) Patients with AN (n = 26) Controls (n = 23, allwomen) Patients with AN-R (n = 40) Patients with AN-BP (n = 23) Controls (n = 20, allwomen) Patients with AN (n = 18) Controls (n = 19, allwomen) Patients with AN (n = 64) Controls (n = 80, allwomen) Patients with AN, (n = 43) Controls (n = 39, allwomen) Patients with low weight (n = 17) Controls (n = 77, allwomen) Patients with AN (n = 19) Controls (n = 19, allwomen) Patients with AN (n = 38 women/2 men) Controls (n = 38 women/2 men)

Rapps

2010 3b

Observational,

et al 946

cross-sectional, case-control

Schecklmann et al 947

2012

3b

Observational,

SS-TDI

cross-sectional, case-control

Bottle threshold and discrimination test

Stein

2012

4

Observational,

et al 956

cross-sectional, case-control

Dazzi

2013

4

Observational,

SS-TDI

et al 948

cross-sectional, case-control

SS-TDI

Fernández -Aranda et al 949*

2016

3b

Observational,

cross-sectional, case-control

Bentz

2017

3b

Observational,

SS-IDandT

et al 950

cross-sectional, case-control

SS-TDI

Fernandez Garcia et al 951*

2017

3b

Observational,

cross-sectional, case-control

Tonacci

2019

3b

Observational,

SS-TDI extended No relevant difference in OF between the AN and control groups

et al 952 †

cross-sectional, case-control

SS-TDI

Kinnaird et al 943

2020 3b

Observational,

cross-sectional, case-control

Islam

2015

3a

Systematic review 14 studies

et al 871

Mai

14 studies

2020 1

Systematic review and meta-analysis

et al 940

AN = anorexia nervosa; BMI = body mass index; B-SIT = Brief Smell Identification Test; CCCRC = Connecticut Chemosensory Clinical Research Center; ETOC = European Test of Olfactory Capabilities; LOE = level of evidence; OD = olfactory dynsfunction; ODT = odor detection threshold; OF = olfactory function; OLFACT = Olfactory Function Assessment by Computerized Testing; SS-ID = Sniffin’ Sticks identification only; SS-T = Sniffin’ Sticks threshold only; SS-TDI = Sniffin’ Sticks threshold, discrimination, identification combination; UPSIT R = University of Pennsylvania Smell Identification Test.