April 2020 HSC Section 4 - Plastic and Reconstructive Problems

J A M A CAD D ERMATOL J ULY 2017

Adil and Godwin

Results, mean difference hair density/cm 2 (SD) * between baseline and follow-up

Continued

26 Hairmax: 17.3 (12.1) Placebo: 2.1 (18.1)

16 LLLLT: 17.7 (25.7) Placebo: 0.06 (23.3)

Placebo: 0.58 (SEM = 2.05)

26 Minoxidil 5%: 12.32 (SEM = 2.05)

Placebo: 2.1 (7.4)

16 Minoxidil 5%: 20.9 (22.5) Placebo: 4.7 (19.7)

24 LLLLT: 16.6 (9.3)

Follow-up, weeks

Supplementary Table I. Details of studies included in the review Article Sex Study population details Intervention group Control LLLLT (Hairmax Laser Comb) 655 nm N = 71 Sham device N = 39 LLLLT

shampoo N = 50

Placebo

N = 19

Placebo

N = 6

Placebo

N = 172

Placebo

630 nm, 650 nm, and 660 nm N = 9

Minoxidil 5% topical foam applied twice daily N = 180

Minoxidil 5% topical solution (1 mL)

applied twice daily plus placebo shampoo N = 50

655 nm

N = 22

LLLLT

Leavitt et al 2009 9 Men Mean age: 47.9 years Exclusion: use of medications 6 months reduction, current hair weave, or tattooing of the alopecic area Race: 90% white AGA type: NH type IIa-V Lanzafame et al 2013 10 Men Mean age: 18-48 years Exclusion: N/S Race: N/S before study that could affect hair growth, hair transplantation, scalp

Kim et al 2013 11 Men Mean age: 44.2 years Exclusion: use of medications affecting hair growth within the past 6 months, hair disorders other than AGA, and systemic diseases that might affect results Country: Korean AGA type: NH type III-VII

affect hair growth within past 6 months, chemotherapy within the past year, uncontrolled hypertension, scalp conditions other than AGA, hair

transplants, scalp reduction, or hair weaves Race: 86.6% white AGA type: NH type III-V

Berger et al 2003 13 Men Mean age: 40 years Exclusion: other skin diseases of the scalp, hair loss disorders other than AGA, used products known to influence hair growth in the past 6 months Race: 97% white AGA type: NH type III or IV

Olsen et al 2007 12 Men Mean age: 39.2 years Exclusion: use of medications that may

AGA type: NH type IIa-V

94