April 2020 HSC Section 4 - Plastic and Reconstructive Problems

J A M A CAD D ERMATOL J ULY 2017

Adil and Godwin

16 Minoxidil 2%: 19.57 ( P # .05) Placebo: 13.04 ( P # .05)

Results, mean difference hair density/cm 2 (SD) * between baseline and follow-up

Continued

32 Minoxidil 2%: 50.14 (29.76) Placebo: 20.64 (21.3)

48 Minoxidil 2%: 12.7 (20.7) Placebo: 3.9 (21.7)

24 Minoxidil 2%: 10.68 (6.26) Placebo: 2.96 (4.01)

24 Minoxidil 2%: 79 (202.1) Placebo: 30 (163.6)

16 Minoxidil 2%: 29.8 (19.35) Placebo: 22.5 (20.34)

Follow-up, weeks

Article Sex Study population details Intervention group Control Placebo N = 14

Placebo

N = 71

Placebo

N = 11

Placebo

N = 18

Placebo

N = 83

Placebo

N = 44

(1 mL) applied twice daily N = 14

Minoxidil 2% twice daily N = 139

(1 mL) applied twice daily N = 11

(1 mL) applied twice daily N = 17

(1 mL) applied twice daily N = 80

(1 mL) applied twice daily N = 41

Minoxidil 2% topical

Minoxidil 2% topical

Minoxidil 2% topical

Minoxidil 2% topical

Minoxidil 2% topical

Exclusion: receiving hormonal therapy, use of medication that could affect hair

growth within the preceding 3 months, anemia, iron deficiency, thyroid disease Race: N/S AGA type: Ludwig grade I or II

Olsen et al 2002b 14 Men Mean age: 36.5 years Exclusion: systemic illness, hypersensitive to minoxidil, concomitant use of hair restorers or systemic drugs

Race: 79% white, 17% Hispanic, 1.5% black, 1.3% Asian, 1.2% other AGA type: pattern 3-6 on Savin Scale AGA type: N/S

Shupack et al 1987 20 Men Mean age: 33 years Exclusion: chronic disease, concomitant dermatologic disorders of the scalp Race: N/S AGA type: NH type III-IV Roberts 1987 21 Men Mean age: 35 years Inclusion: N/S Race: N/S

Exclusion: cardiovascular disease; dermatologic problems of scalp; liver, kidney, or endocrine disease; previous Exclusion: heart disease Race: 88% white

topical minoxidil use; antihypertensives or hair restorers Country: Germany AGA type: NH type III-IV AGA type: NH type IIIv-VI

Petzoldt et al 1988 22 Men Mean age: 32.9 years

Olsen et al 1985 23 Men Mean age: 36.2 years

Supplementary Table I. Cont’d

Olsen 1991 19 Women Mean age: 37 years

96