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Wise et al.

Page 372

Author Manuscript Author Manuscript Author Manuscript Author Manuscript

Study Year LOE Study design Study groups Clinical endpoint Conclusion 2 2 mL methylprednisolone acetate (40 mg/mL) Aasbjerg et al. 1255 2013 4 Retrospective study of Danish National Registries between 1995 and 2011 Incidence and relative risk of osteoporosis, diabetes, tendon rupture, and respiratory tract infection Relative risk and incidence of osteoporosis and diabetes were

higher in individuals receiving at least 1 depot corticosteroid injection vs those receiving immunotherapy.

Patients receiving IM steroid injections in April–July or immunotherapy against grass or birch pollen (n = 47,382)

ACTH = adrenal corticotropic hormone; IM = intramuscular; LOE = level of evidence; PAR = perennial allergic rhinitis; PO = per os (medication taken orally); SAR = seasonal allergic rhinitis.

Int Forum Allergy Rhinol . Author manuscript; available in PMC 2020 June 10.