xRead - Nasal Obstruction (September 2024) Full Articles

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KUANetal.

TABLE IX.1 Evidence surrounding the workup of regional and distant metastasis.

Clinical endpoints

Study

Year LOE Study design Study groups

Conclusion

Maurer et al. 198

1. 46.9% hybrid PET exams revealed ARI 2. 33.3% hybrid PET exams revealed CRI 3. Hybrid PET imaging provides ARI and CRI in addition to regional sinonasal/neck MRI 1. Hybrid PET imaging is excellent at identifying regional and distant metastasis 2. Lymph node metastases: 100% sensitivity, 91.7% specificity 3. Distant metastases: 100% sensitivity, 98.3% specificity 1. Negative PET/CT was predictive of absence of disease 2. Positive PET/CT can be falsely positive and should be viewed with clinical vigilance 3. PET/CT had an overall sensitivity and specificity of 90% 4. PET/CT specificity of 92% and NPV of 100% for initial staging of cervical metastasis 5. PET/CT sensitivity of 100% and Pretreatment PET/CT is useful as a baseline to assess response posttreatment and allows for faster identification of cervical and distant metastasis using one imaging modality Minimal axial diameter of 5 mm on MRI is most appropriate for identifying metastatic RPLN 1. 9.5% cervical node involvement 2. 6.5% distant metastasis 3. Distant metastatic workup should be considered regardless of regional nodal status 4. Distant metastasis portends worse survival (Continues) specificity of 92% for initial staging of distant metastasis

1. Additional radiological information (ARI) 2. Clinically relevant information (CRI)

2021

3

Retrospective cohort

75 patients diagnosed with malignant sinonasal tumors; 96 regionalized MRI and hybrid PET scans

Meerwein et al. 217

2021

3

Retrospective cohort

Patients diagnosed with sinonasal cancer and

Diagnostic

accuracy of hybridPET imaging

undergoing hybrid PET imaging for initial staging

( n = 65)

Lamarre et al. 197 2012 3

Utility of PET for tumor staging

Retrospective cohort

PET scans from patients with

sinonasal neoplasms ( n = 31)

Gil et al. 216

2007 3

Prospective cohort

Patients undergoing skull base tumor excision ( n = 47, preoperative PET/CT = 23)

Value of PET–CT to evaluate cervical lymph nodes and distant metastases

Kosugi et al. 202

Radiologic

2021

4

Retrospective case series

Patients who

criteria of metastatic RPLN

underwent MRI before and after treatment of maxillary sinus SCC ( n = 16)

Chweya et al. 203

2021

4

Retrospective database (SEER)

325 patients with ACC 1. OS 2. DSS