xRead - Nasal Obstruction (September 2024) Full Articles

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KUANetal.

TABLE IX.1 (Continued)

Clinical endpoints

Study

Year LOE Study design Study groups

Conclusion

Abraham 208

2015 5

Review/expert opinion

Head and neck cancer patients

N/A

In sinonasal tumors: 1. MRI to assess orbital and intracranial extension 2. US use is limited 3. PET/CT for staging and to assess cervical adenopathy 1. MRI to assess orbital and intracranial extension 2. PET/CT for systemic staging and cervical adenopathy has superior sensitivity and specificity for nodal staging than anatomic modalities 1. Neck palpation should be performed on physical exam to look for enlarged cervical lymphadenopathy 2. MRI to assess brain metastasis 3. CT chest, abdomen, and pelvis and PET/CT to assess distant metastasis PET–CT: Indications not clearly defined. Useful for patients with suspected metastasis. 1. Neck palpation should be performed on physical exam to look for enlarged cervical adenopathy 2. CT neck and chest is indicated for staging of regional and distant metastasis 3. No consensus on PET/CT, but can be used for initial staging 1. Cervical nodal metastasis: - CT: NPV 84%, PPV 50% - MRI: NPV 79%, PPV 52% - PET: sensitivity 80%–96%; specificity 90%–94% 2. CT and MRI are similar in accuracy in identifying cervical nodal metastasis 3. PET: Useful for staging regional and distant metastasis

Antoniou 211

2014 5

Review/expert opinion

SNM

N/A

Gilain et al. 213

2014 5

Review/expert opinion

Nasal and paranasal SNMM

N/A

Llorente et al. 98

2014 5

Review/expert opinion

Sinonasal carcinoma N/A

Jegoux et al. 215

2013 5

Review/expert opinion

Paranasal sinus cancers

N/A

Rankin 209

2003 5

Review/expert opinion

Imaging in malignant sinus tumors

N/A

Abbreviations: CT, computed tomography; FNAB, fine-needle aspiration biopsy; LN, lymph node; MRI, magnetic resonance imaging; NPV, negative predictive value; ONB, olfactory neuroblastoma; OS, overall survival; PET, positron emission tomography; PPV, positive predictive value; RPLN, retropharyngeal lymph nodes; SCC, squamous cell carcinoma; SEER, Surveillance, Epidemiology, and End Results; SNM, sinonasal malignancy; US, ultrasound. a LOE downgraded for lack of controlling for confounding factors.