xRead - Nasal Obstruction (September 2024) Full Articles

20426984, 0, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/alr.23262, Wiley Online Library on [02/01/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License

356

KUANetal.

TABLE XXXII.2 (Continued)

Clinical endpoints

Study

Year LOE Study design Study groups

Conclusion

McCoul et al. 2116 2012 3

1. SNOT-22 scores worsened initially postoperatively but improved by 1 year 2. GTR and type of grafting material predicted improved SNOT-22 scores at later follow-up 3. There was strong correlation between SNOT-22 and ASBQ scores 1. There was a significant improvement in SNOT-22 scores over time from 1 to 3 and > 12 months after surgery 2. More than 75% of patients achieved their best postop SNOT-22 scores by 12 months 3. Patients identified loss of smell/taste, nasal obstruction, postnasal drip, waking up at night, and lack of a good night’s sleep as the most important items affecting their health 1. There was a 5% postoperative mortality rate and a 36% postoperative complication rate including wound complications (20%), CNS complications (16%), systemic complications (5%), and orbital complications (2%) 2. Medical comorbidities, prior RT, dural invasion, and brain invasion were associated with complications Mean SNOT scores for difficulty falling asleep, difficulty with nasal breathing, waking up at night, waking up tired, and frustration/restlessness/irritability improved postoperatively, whereas olfactory function worsened 1. 45% of those with unilateral surgery had preserved olfaction versus 0% with bilateral 2. There was no association between reconstruction technique or adjuvant therapy with olfaction 3. Median SNOT-22 values were equivalent in both groups 1. Six (43%) patients had residual smell function, with two having near-normal to normal function 2. No cases had disease recurrence

Health-related QOLas

Prospective cohort

85 patients undergoing endoscopic skull base surgery for a varietyof pathologies

measured by the SNOT-22 andASBQ

Pant et al. 2115

2010 3

Prospective cohort

51 patients undergoing endonasal skull base surgery for a variety of skull base lesions

Health-related QOLas

measured by the ASBS and SNOT-22

Ganly et al. 2056

Postoperative

1193 patients

2005 3

Multicenter

mortality and complications

undergoing open craniofacial resection of malignant tumors of the skull base

retrospective cohort

Sunet al. 2111

2021 4

Retrospective case series

26 patients undergoing EEA of Kadish C

Preoperative and 6-month postoperative SNOT-22 scores

ONB, with RT ( n = 25) and/or chemotherapy ( n = 16)

Schreiber et al. 374

1. Olfaction, taste, and QOL 2. Functional outcomes

2018 4

Retrospective case series

54 patients with ITAC treated with unilateral ( n = 27) or bilateral ( n = 27) endoscopic resection

Tajudeen et al. 1361

2016 4

Retrospective case series

14 patients undergoing unilateral ONB resection (seven received postoperative RT)

Olfaction

(UPSIT)

(Continues)