xRead - Nasal Obstruction (September 2024) Full Articles

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355

ICAR SINONASAL TUMORS

TABLE XXXII.2 (Continued)

Clinical endpoints

Study

Year LOE Study design Study groups

Conclusion

1. Malignant tumors were associated with worse ASBQ and SNOT-20 scores 2. T3/T4 tumor stage and postoperative CRT were associated with worse ASBQ and SNOT-20 scores 3. There was no significant difference between patients undergoing open and endoscopic resection 1. There was no significant difference between patients with and without NSF on the SNOT-22 or NSS 2. Patients who received adjuvant RT had higher postoperative SNOT-22 and NSS than those who did not 1. SNOT-22 and NSS did not significantly change from pre- to postoperatively 2. Endoscopic evaluation revealed worsened postoperative scores compared to preoperatively for both flap- and nonflap sides, though this did not appear to affect QOL outcomes 1. In patients with SNM, there was no change in mean overall SNOT-20 score from baseline to 6 months 2. Improvement was only seen in the sleep subdomain 3. There was improvement in SNOT-20 scores from baseline to 6 months in patients not receiving adjuvant treatment, but not in those who did 1. 75% had improvement or no change in QOL postoperatively 2. Improved scores were found in the physical symptom domain and worse scores were found in the specific symptom domain postoperatively 3. Most common symptoms were impaired smell, loss of appetite, nasal secretions, epiphora, visual disturbances, and interference with social, work, and family life 4. Female patients reported lower scores than the males in all domains (Continues)

QOLas

Deckard

2015 3

Prospective cohort

Patients with benign ( n = 39) and malignant ( n = 32) sinonasal and skull base neoplasms

et al. 2085

measured by the SNOT-20, ASBQ, and EQ-5D

Harvey et al. 2130 2015 3

Prospective cohort

118 patients with skull base tumors, including 34% with malignant tumors

SNOT-22 and NSSat

baseline and at last follow-up

undergoing endoscopic

resection with NSF ( n = 42) or without NSF ( n = 76) 36 patients undergoing endoscopic anterior skull base surgery withNSF reconstruction

Hanson et al. 2131 2015 3

SNOT-22 scores, NSS, and endoscopic

Prospective cohort

evaluation at baseline and 90 days post operatively

Harrowand Batra et al. 2089

2013 3

Prospective cohort

94 patients undergoing endoscopic resection of benign ( n = 45) and malignant ( n = 49) sinonasal tumors

1. Preop QOL 2. Postop QOL

Cavel et al. 2128

QOLas

2012 3

Retrospective cohort

41 patients with skull base tumors undergoing EEA

measured by theASBQ administered within 6months of surgery