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260

International consensus statement on rhinosinusitis

Atopy was significantly more prevalent in patients with asthma (85%) than in

CRSwNP patients without asthma (66%).

The prevalence of asthma was 36% in CRSsNP vs 56% in CRSwNP. Comorbid

asthma was associated with severity in CRSwNP.

Asthma was associated with increased risks of CRSwNP and CRSsNP.

Patients undergoing ESS reported improved

miniAQLQ and ACT scores at 6months postoperatively.

Prevalence of asthma was 27.8%, and more severe

CRS symptomatology was

associated with comorbid asthma.

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions

characteristics of patients

with AERD to those with CRSwNP alone, asthma

alone, or both CRSwNP and asthma.

conditions, and radiologic sinus severity

Association between asthma and the risk of CRS

The impact of CRS or ESS upon asthma QoL and asthma control using

validated outcome metrics

characteristics and their associations with CRS symptom severity

Compared the clinical

Demographics, comorbid

Prevalence of CRS

Chen 199 2016 3 Population-based survey 81,462 patients with a mean ± SD follow-up period of 5.8 ± 2.4years.

Stevens 198 2017 3 Case series study 459 patients with CRSwNP alone, 412 with both

CRSwNP and asthma, 171

with AERD, and 300 with asthma only

507 patients with CRSsNP and 874 with CRSwNP

86 patients with CRS comorbid asthma

Hoehle 200 2018 4 Retrospective review 572 CRS patients in a single rhinology clinic

Benjamin 185 2019 4 Retrospective clinical data review study

Schlosser 192 2017 3 Prospective, multi-center, observational cohort study

TABLE V-4 (Continued)