xRead - Nasal Obstruction (September 2024) Full Articles

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303

Orlandi et al.

Peters 451 2014 5 Guideline No evidence for use of decongestants in

ARS (option, Grade D)

Chow 32 2012 5 Guideline Recommend against use of oral/topical decongestants in ABRS (strong

recommendation, low-moderate evidence)

difference among the groups

decongestant use in ABRS based on

Grade D evidence, first principles

TABLE VII-14 Evidence for decongestants in ARS treatment Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Wiklund 449 1994 2 DBRCT Patients with acute maxillary sinusitis treated with phenoxymethyl-penicillin and: Oxymetazoline Placebo Clinical examination through 28 days Sinus X-ray VAS entries in patient diary No difference between groups MCC No significant

Rosenfeld 88 2015 5 Guideline Discourage

Fokkens 26 2020 5 Guideline No recommendation

Inanli 417 2002 3 RCT ABRS patients (ages 12-75) treated with amoxicillin/clavulanic acid and: No topical treatment INCS Oxymetazoline Hypertonic saline Normal saline