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342

International consensus statement on rhinosinusitis

Catalano 655 2007 4 Prospective case series CRS patients undergoing ESS SPECT, Histopathology SPECT sensitive for detecting osteitis on histopathology. Cho 651 2006 4 Retrospective case series CRS patients undergoing primary ESS Lund-Mackay score, CT (HU), histopathology Kim 658 2006 4 Retrospective case series

surgery and CRSwNP. No

correlation between QoL and neo-osteogenesis.

Neo-osteogenesis may predict less post-op QoL improvement.

Patients with hyperostosis (64%) more likely to have poor outcomes.

Neo-osteogenesis associated with need for oral steroid post-op.

formation, and ethmoid bone density were

significantly higher in the revision surgery group.

Eosinophilia is associated with neo-osteogenesis, symptoms do not correlate.

HU were increased with high grade histopathology.

Neo-osteogenesis based on CT in 36% v. pathology 53%. Higher prevalence in revision surgery.

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions

KOS higher with revision

LM scores, new bone

histopathology, endoscopy,

Lund-Mackay, QoL

histopathology, SNOT22 Lund-Mackay score, Endoscopy, CT

neo-osteogenesis,

Symptom scores

CT scans for hyperostosis, postoperative endoscopic outcomes CTscan for

Radiographic osteitis scores, SNOT22,

endoscopic scores, steroid use KOS,GOSS

formation, Bone density (HU)

Lund-Mackay scores, endoscopy,

neo-osteogenesis, histopathology

CT scores, New bone

Radiographic osteitis,

Sacks 659 2013 4 Prospective case series CRS patients undergoing primary ESS (n = 53)

CRS patients undergoing primary (n = 25) and revision (n = 15) surgery, controls (n = 25)

Snidvongs 661 2013 4 Retrospective cohort CRS patients undergoing surgery (n = 88)

undergone primary ESS (n = 81)

CRS patients undergoing ESS (n = 88)

Bhandarkar 639 2011 4 Prospective case series CRS patients undergoing ESS

Lee 640 2006 4 Prospective case series CRS patients undergoing ESS

CRS patients having

Snidvongs 254 2012 4 Retrospective case series

Cho 660 2008 4 Retrospective case control

TABLE IX-6 (Continued)