xRead - Nasal Obstruction (September 2024) Full Articles

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346

International consensus statement on rhinosinusitis

tissue with rtPCR, anti- H. pylori Ig or with ELISA on PCR in study group, not detected in controls ( p < 0.001 H. pylori specific IgA

H. pylori DNA is found in

H. pylori DNA/RNA H. pylori present in 4/12 CRS

Higher prevalence of PARE and nasal pepsin in CRS patients.

Patients with refractory CRS post-ESS have more reflux events at all studied anatomic sites; largest

difference is NPx reflux.

Higher prevalence of PARE in CRS.

28.57% of nasal polyp tissue

CRS group with more esophageal, but not

hypopharyngeal reflux events.

patients and 0/13 controls.

and IgG antibodies more

commonly found in CRS patients.

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Vceva 699 2012 4 Case control

triple-probe pH monitoring at NPx, UES, (pH events < 4 and 5), and distal esophagus (pH < 4)

monitoring (double-pH probe): event number, fraction of time pH < 4

Presence of intranasal H. pylori detected in nasal

dual-probe pH monitoring 24 hours pH probe

PARE documented around UES, LES

PARE with 24 hours

PARE with 24 hours

= 12)

Controls (no CRS, no ESS; n = 20) = 11)

Jecker 683 2006 4 Case-control Chronic polypoid RS, prior ESS (n = 20) Healthy volunteers (n = 20)

Mucosa from controls with concha bullosa (n = 13) Healthy controls (n = 11)

Controls (n = 20)

CRS (n = 33)

DelGaudio 676 2005 4 Case-control Post-ESS with inflammation (n = 38)

Post-ESS sans inflammation (n = 10)

Ozdek 701 2003 4 Case-control Mucosa from CRS patients (n Ulualp 684 1999 4 Case-control Refractory CRS (n

Adults with intranasal polyposis 30 controls with concha bullosa

Ozmen 682 2008 4 Case-control

TABLE IX-7 (Continued)