xRead - Nasal Obstruction (September 2024) Full Articles

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International consensus statement on rhinosinusitis

(Continues)

Improved surgical outcomes among CRS patients without asthma (vs with).

Asthmatics have improved FEV1 and decreased medication utilization following ESS.

ESS is associated with improved PROMs and decreased utilization

of asthma control medications, but not objective measures of pulmonary function.

Both medical and surgical treatment of CRS is associated with subjective and objective improvements in asthma.

ESS improves asthma control, as measured by increased FEV1.

Decreased corticosteroid use noted in a subset of patients with asthma.

QoL (SNOT-22) Among all CRS patients undergoing ESS, those with nasal polyps and/or asthma experience the

largest improvement in QoL (as measured by total SNOT-22 score) at 1 and 3 months after surgery

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions

Asthma control (peak flow and medication utilization)

Sinonasal symptoms (VAS)

Asthma and sinonasal questionnaires Spirometry

Bronchodilator and corticosteroid utilization

Changes from baseline to 12 months in: Asthma control and reported symptoms

FEV1, FENO, and peak flow Medication use Hospitalization

Six-month pre and post-operative evaluation of:

Peak expiratory flow

Corticosteroid utilization Sinonasal VAS

CRS patients undergoing ESS with or without asthma

Patients with CRSwNP and asthma undergoing ESS

Asthma and CRS patients treated with ESS or appropriate medical treatment

comorbid CRS undergoing

ESS under local anesthesia vs control

Adults with CRS and asthma undergoing ESS

Asthma patients with

observational trial

observational trial

Ragab 170 2006 2 Nested analysis of RCT

observational trial

Zhang 1363 2014 3 Retrospective review

Dejima 1368 2005 2 Prospective

Uri 1359 2002 2 Prospective

Ikeda 1369 1999 2 Prospective

TABLE X-3 (Continued)