xRead - Nasal Obstruction (September 2024) Full Articles

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Orlandi et al.

ESS demonstrates a beneficial effect on sinonasal and asthma

symptoms. Subset of patients with AERD have inferior upper and

lower airway uptcomes compared to those without aspirin sensitivity. Nonreversible airflow obstruction appears over a 4-yr follow-up

ESS is associated with improved measures of asthma control among CRS patients with and without nasal polyps.

ESS is associated with improved symptom scores and decreased utilization of asthma control

medications and ED presentations among patients with comorbid asthma.

Postoperative improvements in asthma symptom scores, peak expiratory flow, sinonasal

outcomes including olfaction, and QoL are generally maintained at 12-months.

period in medically recalcitrant CRSwNP patients requiring ESS.

ESS is associated with long-term improvement in asthma control, as measured by patient symptoms,

utilization of control medications and frequency of acute exacerbations.

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions PROMs (SF-22,

Objective measures (CT scores, PFTs,

corticosteroid and ED utilization)

flow, rescue medication requirements and hospitalizations)

Number of emergency visits

dyspnea/cough VAS, olfaction score)

Objective measures (peak nasal and pulmonary expiratory flow, spirometry, NPS, butanol test

Lower airway symptoms, spirometry and responsiveness

observational trial Patients with CRS and asthma Asthma symptom score Asthma exhacerbations Utilization of Asthma control medication

Subjective symptoms

Asthma control (peak

Symptom scores

Medication utilization

Sinonasal symptoms

Adults with CRS and asthma undergoing ESS ( ∼ 50% AERD)

undergoing ESS for CRS with or without NP

Adults with CRS and asthma undergoing ESS

Patients with CRSwNP and asthma undergoing ESS

Patients with CRSwNP and asthma undergoing appropriate medical

therapy with or without ESS

Dunlop 171 1999 3 Retrospective Patients with asthma

Batra 1370 2003 3 Retrospective review

observational study

Ehnhage 1362 2012 3 One-year follow-up ofRCT

observational trial

Lambli 1371 2000 3 Prospective

Nishioka 1373 1994 3 Prospective

Senior 1372 1999 3 Prospective

TABLE X-3 (Continued)