xRead - Nasal Obstruction (September 2024) Full Articles

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462

International consensus statement on rhinosinusitis

CRSwNP and AFRS have reduced sinonasal 1 α

(Continues)

hydroxylase and 1,25VD3. Reduction in 1 α hydroxylase

Lower serum and sinonasal 25VD3 in CRSwNP than controls.

Cigarette smoke associated with lower 25VD3 level, impairs conversion to 1,25VD3.

associated with subjective

disease severity in CRSwNP. No difference in serum 1,25

VD3 between CRSwNP and controls. Sansoni 726 2015 4 Case-Control 12Control 31CRSsNP 14CRSwNP Serum 25VD3

insufficiency/deficiency is common in CRSwNP, especially in African Americans.

and AFRS. No difference in serum calcium between

groups. Phosphate is higher in controls and CRSsNP

when compared to AFRS and CRSwNP patients. Schlosser 715 2016 4 Case-Control 18Control 13CRSwNP 13CRSsNP 6AFRS Sinonasal 1 α hydroxylase

correlated with RANTES

and bFGF in CRSwNP. No significant difference in

Serum 25VD3 in CRSwNP and controls. Mulligan 719 2014 4 Case-Control 21 Control (CSF

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Mostafa 716 2016 4 Case-Control 19Control 25AFRS Serum 25VD3 Calcium

25VD3 is lower in CRSwNP

Serum 25VD3 is inversely

Schlosser 1415 2014 4 Retrospective Case Series 70CRSwNP Serum 25VD3 level Serum 25VD3

Serum and sinonasal 25VD3

Sinonasal CYP27B1 gene expression Sinonasal 25VD3 to

1,25VD3 conversion

Nasal MCP-1, RANTES, and bFGF levels

Sinonasal 1,25VD3 SNOT22

Serum 1,25VD3

Phosphate

leak/pituitary tumor patients) 40CRSsNP 45CRSwNP

15CRSwNP

15CRSsNP

TABLE X-8 (Continued)