xRead - Nasal Obstruction (September 2024) Full Articles

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526

International consensus statement on rhinosinusitis

(Continues)

AFRS associated with younger age of presentation, higher

levels of serum IgE levels, and lower prevalence of asthma. AFRS can present with unilateral disease.

Mukherji 1703 1998 4 Retrospective review Patients with AFRS Clinical data AFRS was more common in males and in those from southern US states. deShazo 1720 1995 4 Retrospective case series Patients diagnosed withAFRS Clinical data Proposal of 5 diagnostic criteria forAFRS. Bent 1694 1994 4 Prospective case series Patients diagnosed withAFRS Clinical and pathologic data Defined diagnostic criteria for AFRS. Histopathologic Evaluation Wise 1721 2008 2 Prospective case control study w blinded analysis Control group AFRS CRSsNP IHC of mucosa biopsied from the OMC assessing for IgE AFRS mucosa had significantly more IgE compared to other groups.

IgE was increased more within subepithelial sites when compared to epithelium; Elevated IgE was not fungal-specific.

Charcot-Leyden crystals, bony erosion, type 1 hypersensitivity and

heterogenous opacity with sinus cavity expansion.

geographically with higher incidence in the southern more humid regions.

AFRS Clinical data AFRS prevalence varied

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions

AFRS associated with

Clinical and immunologic data

Clinical and pathologic data

EMRS (n = 69)

AFRS (n = 431)

Saravanan 1718 2006 4 Cross-sectional study CRS patients categorized by presence of

eosinophilic mucin with or without

fungal elements

and retrospective case series

literature review

Ferguson 1719 2000 4 Literature review

Ferguson 1701 2000 4 National survey;

TABLE X-30 (Continued)