xRead - Nasal Obstruction (September 2024) Full Articles

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531

Orlandi et al.

Hypertrophic sinus disease HLA DNA genotyping 66% of AFRS patients carried at least 1 HLA-DQB * 03allele. Allelic variants differed between the 2 groups.

Majority of patients were African American with

higher prevalence of bone erosion in males.

Lower socioeconomic status was associated with more severe disease.

African American. Males had higher prevalence of bone erosion. Socioeconomic

factors did not significantly

correlate with bone erosion.

38 genes were differentially expressed in AFRS vs controls.

Age of presentation was lower for AFRS compared to CRSwNP and CRSsNP.

counties with higher poverty level vs CRSsNP.

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Orlandi 1730 2007 2 Prospective case control AFRS EMRS control AFRS

Majority of patients were

AFRS patients resided in

socioeconomic factors Measures of disease severity

socioeconomic factors

Gene expression profiles in NP tissue using microarray analysis

socioeconomic factors

Demographic and

Ghegan 1698 2007 4 Retrospective chart review AFRS Demographic and

Demographic and

Patients who met 3 of 5 AFRS Bent-Kuhn diagnostic criteria

AFRS

CRSwNP

CRSsNP

Schubert 993 2004 4 Prospective case control

Demographic and Socioeconomic Factors Miller 1700 2014 4 Retrospective case series

Wise 1699 2008 4 Retrospective chart review

TABLE X-30 (Continued)