xRead - Nasal Obstruction (September 2024) Full Articles

20426984, 2021, 3, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/alr.22741 by Stanford University, Wiley Online Library on [01/07/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License

566

International consensus statement on rhinosinusitis

(Continues)

-postop satisfaction depends on ESS improving their most important symptoms. -postoperative satisfaction not correlated to achieving MCID, but correlated to change in SNOT-22 (r = 0.35, p < 0.05).

Across all studies (n = 40) showed a significant change in mean SNOT-22 12.7

44.8pt post-ESS (mean 24.4pt change). All studies showed average improvement that meets MCID.

Nasal obstruction very important symptom by 93% of patients.

TABLE XII-11 Evidence for patient selection and achievement of MCID in sinus surgery for CRS Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Le 1352 2018 1 Systematic review and meta-analysis 3048 CRSwNP pts treated with ESS SNOT-22 Mean SNOT-22 change of 23.0 points (95% CI, 20.2-25.8). Higher preop SNOT-22 scores correlate with greater changes in SNOT-22 scores. Age, asthma, prior ESS correlate with greater improvement in SNOT-22 Tobacco and length of follow up associated with less SNOT-22 change. Soler 1938 2018 1 Systematic review and meta-analysis CRS pts undergoing ESS Change in SNOT-22 and factors that affect SNOT-22 change Smith 1816 2010 2* Prospective, multi-center cohort study CRSwNPand CRSsNP 302pts RDSI and CSS Medical short form − 36 (MSF-36)

72% pts with poor baseline QoL (defined by exclusion of top quintile of QoL scores to avoid ceiling effect) reached clinically

significant change for RSDI and 76% for CSS. Patients undergoing primary ESS were 1.8x (CSS) and 2.1x (RSDI) more likely improve compared to those undergoing revision ESS.

SNOT-22, patient satisfaction

questionnaires

undergoing ESS

100CRSpts

Mattos 1948 2019 3 Prospective cohort study