xRead - Nasal Obstruction (September 2024) Full Articles

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568

International consensus statement on rhinosinusitis

Revision surgery rate was lower in those who achieved the MCID (11.3%) compared with those who did not (18.0%), p < 0.001. Achievement of MCID Pre-op SNOT-22 score > 30 pts have a > 75% chance of achieving an MCID. Pre-op SNOT-22 > 20 required for > 50%chance of achieving MCID. Change in SNOT-22 post-op,

Change in SNOT-22 score 3 months post-op Pre-op SNOT-22 score > 30 pts have a > 70%

104 pts undergoing ESS, CRS w and w/oNP SNOT22 SNOT-22 > 30 absolute improvement post-ESS 13.6-18.3 pts (95% CI).

SNOT-22 < 20 have 37.5% of achieving an MCID with relative mean worsening of QoL No difference in NP subgroup. 73% improvement in RSDI vs 76% CSS post-ESS clinically significant.

Improvement postoperative SNOT-22 reached MCID across all ages. MCID for change in health utility value

exceeded for all ages except age 70-80 years old following ESS.

chance of achieving MCID. CRSwNP had greater improvement than CRSsNP.

Greater improvement following surgery vs medical management.

All groups achieved MCID at 3 months. High baseline scores in the psychological-sleep domain group had worse SNOT-22 outcomes at 6 months.

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Hopkins 1934 2015 3 Prospective observational

post-ESS at 12, 24 months

Mean change in RSDI and CSS

achievement of MCID

Lehmann 1943 2018 3 Prospective cohort study 636 CRS patients SNOT-22, EQ-5D

SNOT-22,

327 pts refractory CRS patients undergoing ESS,

grouped based on pre-op SNOT22

score, with polyp subgroup

2263 CRSwNP and CRSsNP

CRS w and w/o NP post-ESS 75pts

ESS divided into 4

clusters based on preoperative

SNOT-22 scores

146 pts undergoing

observational

cohort study

Kennedy 1944 2013 4 Retrospective case series

cohort study

Smith 1936 2011 3 Prospective, cohort study

Lal 1176 2018 4 Retrospective case series

Rudmik 1940 2015 3 Prospective

TABLE XII-11 (Continued)

*Upgraded due to multicenter study with common disease definition and outcome metrics.