xRead - Nasal Obstruction (September 2024) Full Articles

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International consensus statement on rhinosinusitis

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TABLE XII-13 Evidence for preoperative corticosteroid administration in CRSwNP Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions Hwang 1966 2016 1 Meta-analysis CRSwNP treated with preoperative steroid Intraoperative bleeding, surgical field visibility and operative time The treatment of preoperative steroid can reduce intraoperative bleeding, improve surgical field and decrease surgery time Pundir 1965 2016 1 Systematic review of randomized trials CRSsNP and CRSwNP treated with 4-week course of mometasone furoate Intraoperative blood loss Statistically significant reduction in blood loss on Boezaart score Ecevit 1616 2015 2 Prospective double blinded RCT CRSwNP who were refractory to topical treatment treated with 60 mg prednisolone then reduce 10 mg every other day and stop after 10 mg for 2 days Visual analog scale (VAS), polyp score, Lund-Mackay score, Connecticut Chemosensory Clinical Research Center butanol olfactory threshold test, peak nasal inspiratory peak flow (PNIF), bleeding scoring The therapy of steroid can decrease intraoperative bleeding, surgery time, improve operative field and reduce the time in hospital Günel 1968 2015 2 Individual double blinded RCT CRSwNP treated with oral prednisolone (1 mg/kg) once daily for 2 days then tapered off Mean bleeding volume, surgical field quality scores, Lund-Kennedy score, Lund-Mackay score, nasal polyp size and Kennedy Osteitis Scores There was no significant change on intraoperative bleeding and surgical field after preoperative corticosteroid