xRead - Nasal Obstruction (September 2024) Full Articles

20426984, 2021, 3, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/alr.22741 by Stanford University, Wiley Online Library on [01/07/2024]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License

571

Orlandi et al.

Atighechi 1967 2013 3 Individual open CRSwNP treated with 5 day course or single dose of systemic corticosteroid Surgical field quality Better surgical field following treatment Sieskiewicz 1952 2006 3 Individual open Blood loss and label-controlled trial

improvement in mucosal status and surgical difficulty

INCS use was associated with increased blood loss during surgery

reduction in blood loss and operation time Statistically significant

increase in blood loss with no difference between CRSsNP and CRSwNP

reduction in blood loss

Study Year LOE Study Design Study Groups Clinical Endpoint Conclusions

Statistically significant

Statistically significant

Statistically significant

Mucosal status and difficulty during surgery

Intraoperative blood loss

Intraoperative blood loss and operation time

Intraoperative blood loss

condition of surgical field

CRSwNP treated with 5 day course of 30 mg oral prednisone

Grzegorzek 1963 2014 4 Case series Treatment with systemic or topical corticosteroid

CRSsNP and CRSwNP treated with 4-weeks

of mometasone furoate

Tirelli 1957 2019 3 Prospective cohort CRSsNP and CRSwNP treated with at least 3 months INCS

CRSwNP treated with 5 days of 30 mg oral prednisone

Wright 255 2007 2 Prospective double blinded RCT

Albu 1953 2010 2 Prospective double blinded RCT

label-controlled trial

TABLE XII-13 (Continued)

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