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clarithromycin in chronic rhinosinusitis patients without nasal polyp or with small nasal polyp. Auris Nasus Larynx . 2012;39(1):38-47. 1114. Deng J, Chen F, Lai Y, et al. Lack of additional effects of long-term, low-dose clarithromycin combined treatment com pared with topical steroids alone for chronic rhinosinusitis in China: a randomized, controlled trial. Int Forum Allergy Rhi nol . 2018;8(1):8-14. 1115. Amali A, Saedi B, Rahavi-Ezabadi S, Ghazavi H, Hassanpoor N. Long-term postoperative azithromycin in patients with chronic rhinosinusitis: a randomized clinical trial. AmJ Rhi nol Allergy . 2015;29(6):421-424. 1116. Haxel BR, Clemens M, Karaiskaki N, Dippold U, Kettern L, Mann WJ. Controlled trial for long-term low-dose ery thromycin after sinus surgery for chronic rhinosinusitis. Laryngoscope . 2015;125(5):1048-1055. 1117. Pynnonen MA, Venkatraman G, Davis GE. Macrolide therapy for chronic rhinosinusitis: a meta-analysis. Otolaryngol Head NeckSurg . 2013;148(3):366-373. 1118. Huang Z, Zhou B. Clarithromycin for the treatment of adult chronic rhinosinusitis: a systematic review and meta-analysis. Int Forum Allergy Rhinol . 2019;9(5):545-555. 1119. Soler ZM, Oyer SL, Kern RC, et al. Antimicrobials and chronic rhinosinusitis with or without polyposis in adults: an evidenced-based review with recommendations. IntForum Allergy Rhinol . 2013;3(1):31-47. 1120. Cervin A, Wallwork B. Efficacy and safety of long-term antibi otics (macrolides) for the treatment of chronic rhinosinusitis. Curr Allergy Asthma Rep . 2014;14(3):416. 1121. Seresirikachorn K, Suwanparin N, Srisunthornphanich C, Chitsuthipakorn W, Kanjanawasee D, Snidvongs K. Factors of success of low-dose macrolides in chronic sinusitis: systematic review and meta-analysis. Laryngoscope . 2019;129(7):1510-1519. 1122. Malhotra-Kumar S, Lammens C, Coenen S, Van Herck K, Goossens H. Effect of azithromycin and clarithromycin ther apy on pharyngeal carriage of macrolide-resistant streptococci in healthy volunteers: a randomised, double-blind, placebo controlled study. Lancet . 2007;369(9560):482-490. 1123. Oakley GM, Christensen JM, Sacks R, Earls P, Harvey RJ. Characteristics of macrolide responders in persistent post surgical rhinosinusitis. Rhinology . 2018;56(2):111-117. 1124. Tanner SB, Fowler KC. Intravenous antibiotics for chronic rhi nosinusitis: are they effective? Curr Opin Otolaryngol Head NeckSurg . 2004;12(1):3-8. 1125. Gross ND, McInnes RJ, Hwang PH. Outpatient intra venous antibiotics for chronic rhinosinusitis. Laryngoscope . 2002;112(10):1758-1761. 1126. Fowler K, Duncavage J, Murray J, Tanner S. Chronic sinusi tis and intravenous antibiotic therapy: resolution, recurrence, and adverse events. J Allergy Clin Immunol . 2003;111(2):S85. 1127. Anand V, Levine H, Friedman M, et al. Intravenous antibi otics for refractory rhinosinusitis in nonsurgical patients: preliminary findings of a prospective study. Am J Rhinol . 2003;17(6):363-368. 1128. Tabaee A, Anand VK, Yoon C. Outpatient intravenous antibi otics for methicillin-resistant Staphylococcus aureus sinusitis. AmJRhinol . 2007;21(2):154-158. 1129. Don DM, Yellon RF, Casselbrant ML, Bluestone CD. Effi cacy of a stepwise protocol that includes intravenous antibi