xRead - Olfactory Disorders (September 2023)

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PATEL et al.

TABLE VII.16b Section evidence summary: Related to extremely low or high BMI

Olfactory test method used

Author

Year

LOE Study design Study groups

Conclusions

Related to

extremely high BMI

Guild 968

1956

5

Observational,

Obese patients (n = 5) Controls (n = 5, all women) Patients with BMI < 45 (n = 47 women/8 men) Patients with BMI > 45 (n = 40 women/6 men)

Blast-injection methodby Elsberg and Lewy

There was evidence that controls had greater olfactory acuity than obese patients individuals were more likely than moderately obese individuals to demonstrate B-SIT scores consistent withOD Morbidly obese between BMI and OF: odor detection and identification function were lower in overweight patients than in controls when the agewas < 65 years, whereas in patients ≥ 65 years, functions were better in overweight patients than in controls difference in overall OF was observed in relation to BMI No significant Age-dependent association

cross-sectional, case-control

B-SIT

Richardson et al 963

2004 4

Observational,

cross-sectional, case-control

Simchen et al 971

2006

4

Observational,

Overweight

ETOC

cross-sectional, case-control

patients (n = 87) Controls (n = 226) Five age groups at intervals of 15 years, with 50 to 60 participants

each, all were aged ≥ 20years

Trellakis et al 969

SS-TDI

Obese patients (n = 12) Controls (n = 10) Overweight patients (n = 9) Overweight/obese (n = 21women/6 men) Controls (n = 21 women/6 men) Obese patients (n = 7) Overweight patients (n = 18) Controls (n = 30) Lowweight patients (n = 5)

2010 4

Observational,

cross-sectional, case-control

Zijlstra

2011

4

Observational,

Retronasal aroma release using spiced rice

There were no significant

et al 970

cross-sectional, case-control

differences in recognition of retronasal aroma release between the groups

SS-TDI

Higher BMI was associated with worsened odor

Skrandies et al 958

2015

3b

Observational,

cross-sectional, case-control

threshold function

(Continues)