xRead - Olfactory Disorders (September 2023)

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INTERNATIONAL CONSENSUS ON OLFACTION

TABLE VII.17 Section evidence summary: Related to smoking Author Year Design LOE Study groups

Olfactory indicator Smoking measure Conclusions

Improvement in

Cigarettes per day andyears smoking

SS-TDI extended,

2

28 volunteers who were admitted to a smoking cessation section program and with chemosensory related conditions Average of 22 cigarettesper day smokers (18 to 65 years) with a diagnosis of nonallergic CRS and a cigarette smoking habit for ≥ 5 years Nonallergic CRS, based on clinical evidence, nasal resistances, cytology, and olfactory thresholds Smokers consisted of 22 men and 22 women (mean age = 46years) who averaged 20 cigarettes per day werepast smokers, normosmics (by testing), and those refusing to 70 consecutive Excluded were patients who smokers (n = 1126) and former smokers (n = 3239) were assigned randomly to continue smoking for 2 weeks or to stop smoking smokers and never-smokers were excluded Daily smokers Occasional quit smoking after surgery Adult daily

Dinc,

2020 Prospective cohort, interven tion

et al 983

measured OF as soon as 45 days after smoking cessation, withmore

immediately before smoking cessation and 45 days after smoking cessation

improvements in patients who had

smoked for the fewest years before cessation

Ottaviano et al 984

2012

Prospective, random ized, double blind

2

SS-T (butanol)

Cigarettes per day andyears smoking

Simple, isotonic sodium chloride solution nasal irrigations significantly improved olfactory threshold

Both smokers and nonsmokers with

Pack-years (number of packs smoked per day, number

SS-TDI extended at baseline and 1, 3, and 6 months in a bilateral mode

Danielides et al 985

2009

Prospective cohort

2

massive NPs presented a highly significant improvement in OF during the 6-month postoperative period after ESS, provided that all smokers quit smoking after surgery associated with poorer olfactory thresholds Smokers who abstained from smoking reported improvements in the sense of smell right after quitting as well as improved sense of taste and sore throat Heavy smoking was

of years of smoking)

Etter

2013

RCT

2

Self-reported smell and taste from

Revised Minnesota Withdrawal Scale Cigarettes per day andyears smoking

et al 986

“very poor” to “very good”

(Continues)